Translesion Synthesis or Repair by Specialized DNA Polymerases Limits Excessive Genomic Instability upon Replication Stress.
Genome Surveillance and StabilityMaiorano D, El Etri J, Franchet C, Hoffmann JS
Publications
RNA-sequencing data-driven dissection of human plasma cell differentiation reveals new potential transcription regulators.
Epigenome modifications and genomic instability in normal and malignant B cellsKassambara A, Herviou L, Ovejero S, Jourdan M, Thibaut C, Vikova V, Pasero P, Elemento O, Moreaux J
Immunotherapy perspectives in the new era of B-cell editing.
Epigenome modifications and genomic instability in normal and malignant B cellsUeda N, Cahen M, Danger Y, Moreaux J, Sirac C, Cogné M
Axonal chemokine-like Orion induces astrocyte infiltration and engulfment during mushroom body neuronal remodeling
Neurogenetics and memoryAna Boulanger, Camille Thinat, Stephan Züchner, Lee G. Fradkin, Hugues Lortat-Jacob & Jean-Maurice Dura
TopBP1 assembles nuclear condensates to switch on ATR signaling.
Genetic Instability and CancerFrattini C, Promonet A, Alghoul E, Vidal-Eychenie S, Lamarque M, Blanchard MP, Urbach S, Basbous J, Constantinou A
Exon junction complex dependent mRNA localization is linked to centrosome organization during ciliogenesis
Cell Biology of RNAOh Sung Kwon, Rahul Mishra, Adham Safieddine, Emeline Coleno, Quentin Alasseur, Marion Faucourt, Isabelle Barbosa, Edouard Bertrand, Nathalie Spassky & Hervé Le Hir
A choreography of centrosomal mRNAs reveals a conserved localization mechanism involving active polysome transport
Cell Biology of RNAAdham Safieddine, Emeline Coleno, Soha Salloum, Arthur Imbert, Abdel-Meneem Traboulsi, Oh Sung Kwon, Frederic Lionneton, Virginie Georget, Marie-Cécile Robert, Thierry Gostan, Charles-Henri Lecellier, Racha Chouaib, Xavier Pichon, Hervé Le Hir, Kazem Zibara, Florian Mueller, Thomas Walter, Marion Peter & Edouard Bertrand
Regulation of the conserved 3'-5' exoribonuclease EXOSC10/Rrp6 during cell division, development and cancer.
Mammalian Cell BiologyStuparević I, Novačić A, Rahmouni AR, Fernandez A, Lamb N, Primig M
Splicing-associated chromatin signatures: a combinatorial and position-dependent role for histone marks in splicing definition.
Chromatin and SplicingAgirre E, Oldfield AJ, Bellora N, Segelle A, Luco RF
Anti-prion Drugs Targeting the Protein Folding Activity of the Ribosome Reduce PABPN1 Aggregation.
mRNA Regulation and DevelopmentBamia A, Sinane M, Naït-Saïdi R, Dhiab J, Keruzoré M, Nguyen PH, Bertho A, Soubigou F, Halliez S, Blondel M, Trollet C, Simonelig M, Friocourt G, Béringue V, Bihel F, Voisset C
Modulation of Yorkie activity by alternative splicing is required for developmental stability.
Tubulin codeSrivastava D, de Toledo M, Manchon L, Tazi J, Juge F
Mechanistic analysis of the enhanced RNAi activity by 6-mCEPh-purine at the 5´ end of the siRNA guide strand
Systemic impact of small regulatory RNAsVincent Brechin, Fumikazu Shinohara, Jun-Ichi Saito, Hervé Seitz, Yukihide Tomari
Splicing-associated chromatin signatures: a combinatorial and position-dependent role for histone marks in splicing definition
Biology of distal regulatory elementsAgirre E, Oldfield AJ, Bellora N, Segelle A, Luco RF.
Quantitative imaging of transcription in living Drosophila embryos reveals the impact of core promoter motifs on promoter state dynamics. Nat. Comm, in revision.
Cell Biology of RNAPimmett, L., Dejean, M., Fernandez, C., Trullo, A., Bertrand, E., Radulescu, O., and M. Lagha.
Htt is a repressor of Abl activity required for APP-induced axonal growth
Neurogenetics and memoryClaire Marquilly,Germain U. Busto,Brittany S. Leger,Ana Boulanger,Edward Giniger,James A. Walker,Lee G. Fradkin,Jean-Maurice Dura
TALC: Transcript-level Aware Long-read Correction.
Biology of distal regulatory elementsBroseus L, Thomas A, Oldfield AJ, Severac D, Dubois E, Ritchie W.
Interactions between gut microbiota and skeletal muscle.
Mammalian Cell BiologyGizard F, Fernandez A, De Vadder F
A Role for the Mre11-Rad50-Xrs2 Complex in Gene Expression and Chromosome Organization
Maintenance of genome integrity during DNA replicationForey R, Barthe A, Tittel-Elmer M, Wery M, Barrault MB, Ducrot C, Seeber A, Krietenstein N, Szachnowski U, Skrzypczak M, Ginalski K, Rowicka M, Cobb J, Rando OJ, Soutourina J, Dubrana K, Gasser SM, Morillon A, Pasero P, Lengronne A and Poli J