The kinesin KIF1C transports APC-dependent mRNAs to cell protrusions.
Cell Biology of RNAPichon X, Moissoglu K, Coleno E, Wang T, Imbert A, Robert MC, Peter M, Chouaib R, Walter T, Mueller F, Zibara K, Bertrand E, Mili S
Publications
Replication stress: from chromatin to immunity and beyond.
Maintenance of genome integrity during DNA replicationLin YL, Pasero P
The HSP90/R2TP assembly chaperone promotes cell proliferation in the intestinal epithelium.
Cell Biology of RNAMaurizy C, Abeza C, Lemmers B, Gabola M, Longobardi C, Pinet V, Ferrand M, Paul C, Bremond J, Langa F, Gerbe F, Jay P, Verheggen C, Tinari N, Helmlinger D, Lattanzio R, Bertrand E, Hahne M, Pradet-Balade B
Transcription/Replication Conflicts in Tumorigenesis and Their Potential Role as Novel Therapeutic Targets in Multiple Myeloma.
Epigenome modifications and genomic instability in normal and malignant B cellsDutrieux L, Lin YL, Lutzmann M, Rodriguez R, Cogné M, Pasero P, Moreaux J
Toxic R-loops: Cause or consequence of replication stress?
Maintenance of genome integrity during DNA replicationSamira Kemiha, Jérôme Poli, Yea-Lih Lin, Armelle Lengronne, Philippe Pasero
Stochastic pausing at latent HIV-1 promoters generates transcriptional bursting.
Cell Biology of RNATantale K, Garcia-Oliver E, Robert MC, L\'Hostis A, Yang Y, Tsanov N, Topno R, Gostan T, Kozulic-Pirher A, Basu-Shrivastava M, Mukherjee K, Slaninova V, Andrau JC, Mueller F, Basyuk E, Radulescu O, Bertrand E
A release-and-capture mechanism generates an essential non-centrosomal microtubule array during tube budding.
Tubulin codeGillard G, Girdler G, Röper K
Clinical Correlations of Polycomb Repressive Complex 2 in Different Tumor Types.
Chromatin and cell biologyErokhin M, Chetverina O, Győrffy B, Tatarskiy VV, Mogila V, Shtil AA, Roninson IB, Moreaux J, Georgiev P, Cavalli G, Chetverina D
Chromosome Organization in Early Meiotic Prophase.
Meiosis and recombinationGrey C, de Massy B
3D positioning of tagged DNA loci by widefield and super-resolution fluorescence imaging of fixed yeast nuclei
Maintenance of genome integrity during DNA replicationMégane Da Mota, Julien Cau, Julio Mateos-Langerak, Armelle Lengronne, Philippe Pasero, Jérôme Poli
Cornelia de Lange syndrome-associated mutations cause a DNA damage signalling and repair defect
Nuclear architecture in physiology and pathologyGabrielle Olley, Madapura M. Pradeepa, Graeme R. Grimes, Sandra Piquet, Sophie E. Polo, David R. FitzPatrick, Wendy A. Bickmore & Charlene Boumendil
Chromatin-associated MRN complex protects highly transcribing genes from genomic instability
Gene regulationKader Salifou, Callum Burnard, Poornima Basavarajaiah, Marion Helsmoortel, Victor Mac, David Depierre, Giuseppa Grasso, Céline Franckhauser, Emmanuelle Beyne, Xavier Contreras, Jérôme Dejardin, Sylvie Rouquier, Olivier Cuvier, Rosemary Kiernan
Nucleic Acid Immunity and DNA Damage Response: New Friends and Old Foes.
Molecular Basis of InflammationTaffoni C, Steer A, Marines J, Chamma H, Vila IK, Laguette N
Discovery of candidate DNA methylation cancer driver genes.
Epigenome modifications and genomic instability in normal and malignant B cellsPan H, Renaud L, Chaligne R, Bloehdorn J, Tausch E, Mertens D, Fink AM, Fischer K, Zhang C, Betel D, Gnirke A, Imielinski M, Moreaux J, Hallek M, Meissner A, Stilgenbauer S, Wu CJ, Elemento O, Landau DA
Understanding 3D genome organization by multidisciplinary methods
Chromatin and cell biologyIvana Jerkovic´ & Giacomo Cavalli
In the mouse, prostaglandin D2 signalling protects the endometrium against adenomyosis
Development and Pathology of the gonadPascal Philibert, Stéphanie Déjardin, Nelly Pirot, Alain Pruvost, Anvi Laetitia Nguyen, Florence Bernex, Francis Poulat, Brigitte Boizet-Bonhoure
G9a/GLP targeting in MM promotes autophagy-associated apoptosis and boosts proteasome inhibitor-mediated cell death.
Epigenome modifications and genomic instability in normal and malignant B cellsDe Smedt E, Devin J, Muylaert C, Robert N, Requirand G, Vlummens P, Vincent L, Cartron G, Maes K, Moreaux J, De Bruyne E
A cell-to-patient machine learning transfer approach uncovers novel basal-like breast cancer prognostic markers amongst alternative splice variants.
Biology of distal regulatory elementsVillemin JP, Lorenzi C, Cabrillac MS, Oldfield A, Ritchie W, Luco RF.
A cell-to-patient machine learning transfer approach uncovers novel basal-like breast cancer prognostic markers amongst alternative splice variants
Chromatin and SplicingJean-Philippe Villemin, Claudio Lorenzi, Marie-Sarah Cabrillac, Andrew Oldfield, William Ritchie & Reini F. Luco