Loss of Ezh2 function remodels the DNA replication initiation landscape
Replication and Genome DynamicsPaulina Prorok, Faezeh Forouzanfar, Nerea Murugarren, Isabelle Peiffer, Romain Charton, Ildem Akerman, Marcel Méchali.
Publications
Randomized Phase III Trial Evaluating Subcutaneous Rituximab for the First-Line Treatment of Low-Tumor Burden Follicular Lymphoma: Results of a LYSA Study.
Epigenome modifications and genomic instability in normal and malignant B cellsCartron G, Bachy E, Tilly H, Daguindau N, Pica GM, Bijou F, Mounier C, Clavert A, Damaj GL, Slama B, Casasnovas O, Houot R, Bouabdallah K, Sibon D, Fitoussi O, Morineau N, Herbaux C, Gastinne T, Fornecker LM, Haioun C, Launay V, Araujo C, Benbrahim O, Sanhes L, Gressin R, Gonzalez H, Morschhauser F, Ternant D, Xerri L, Tarte K, Pranger D
Prospective evaluation of lymphoma response to immunomodulatory therapy criteria in GATA trial from the LYSA group.
Epigenome modifications and genomic instability in normal and malignant B cellsAl Tabaa Y, Casasnovas RO, Baillet C, Bachy E, Nicolas-Virelizier E, Schiano De Colella JM, Bailly C, Kanoun S, Guidez S, Gyan E, Gressin R, Morineau N, Ysebaert L, Le Gouill S, Tilly H, Houot R, Morschhauser F, Cartron G, Herbaux C
Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair
Genetic Instability and CancerEmile Alghoul, Matteo Paloni, Arato Takedachi, Serge Urbach, Alessandro Barducci, Pierre-Henri Gaillard, Jihane Basbous, Angelos Constantinou
The small compound Icerguastat reduces muscle defects in oculopharyngeal muscular dystrophy through the PERK pathway of the unfolded protein response.
mRNA Regulation and DevelopmentNaït-Saïdi R, Chartier A, Abgueguen E, Guédat P, Simonelig M
Anti-PD-1 therapy can possibly reverse CAR T cells exhaustion in DLBCL.
Epigenome modifications and genomic instability in normal and malignant B cellsLamure S, Herbaux C
Epigenetic inheritance in adaptive evolution.
Chromatin and cell biologySabarís G, Fitz-James MH, Cavalli G
Identification and Characterisation of Proteins Binding to a G-Quadruplex Origin G-rich Repeated Element in Mammalian Cells
Genome Surveillance and StabilityJames R. A. Hutchins, Isabelle Peiffer, Serge Urbach, Jean-Louis Mergny, View ORCID ProfilePhilippe Marin, Domenico Maiorano, Marcel Méchali
Editorial: Transcriptional control in normal and malignant B-lymphocytes.
Epigenome modifications and genomic instability in normal and malignant B cellsJerome Moreaux, Alexander A Shtil
Cocktails of NSAIDs and 17α Ethinylestradiol at Environmentally Relevant Doses in Drinking Water Alter Puberty Onset in Mice Intergenerationally
Development and Pathology of the gonadPascal Philibert, Stéphanie Déjardin, Mélissa Girard, Quentin Durix, Anne-Alicia Gonzalez, Xavier Mialhe, Mathieu Tardat, Francis Poulat, Brigitte Boizet-Bonhoure
Preventive plasmapheresis for rituximab related flare in cryoglobulinemic vasculitis.
Epigenome modifications and genomic instability in normal and malignant B cellsFornero L, Kanouni T, Tudesq JJ, Pochard C, Verot P, Renier W, Gabellier L, Cartron G, Guilpain P, Herbaux C
Plain Language Summary of the iNNOVATE study: ibrutinib plus rituximab is well-tolerated and effective in people with Waldenström's macroglobulinemia.
Epigenome modifications and genomic instability in normal and malignant B cellsBuske C, Tedeschi A, Trotman J, García-Sanz R, MacDonald D, Leblond V, Mahe B, Herbaux C, Matous JV, Tam CS, Heffner LT, Varettoni M, Palomba ML, Shustik C, Kastritis E, Treon SP, Ping J, Hauns B, Arango-Hisijara I, Dimopoulos MA
Topological screen identifies hundreds of Cp190- and CTCF-dependent Drosophila chromatin insulator elements.
Chromatin and cell biologyKahn TG, Savitsky M, Kuong C, Jacquier C, Cavalli G, Chang JM, Schwartz YB
The BLM helicase is a new therapeutic target in multiple myeloma involved in replication stress survival and drug resistance.
Epigenome modifications and genomic instability in normal and malignant B cells+ Genetic Instability and Cancer / Maintenance of genome integrity during DNA replication
Ovejero S, Viziteu E, Dutrieux L, Devin J, Lin YL, Alaterre E, Jourdan M, Basbous J, Requirand G, Robert N, de Boussac H, Seckinger A, Hose D, Vincent L, Herbaux C, Constantinou A, Pasero P, Moreaux J
Replication gap suppression depends on the double-strand DNA binding activity of BRCA2
Genetic Instability and CancerDomagoj Vugic, Isaac Dumoulin, Charlotte Martin, Anna Minello, Lucia Alvaro-Aranda, Jesus Gomez-Escudero , Rady Chaaban , Rana Lebdy , Catharina von Nicolai , Virginie Boucherit , Cyril Ribeyre , Angelos Constantinou, Aura Carreira
LAIR1, an ITIM-Containing Receptor Involved in Immune Disorders and in Hematological Neoplasms.
Epigenome modifications and genomic instability in normal and malignant B cellsVan Laethem F, Donaty L, Tchernonog E, Lacheretz-Szablewski V, Russello J, Buthiau D, Almeras M, Moreaux J, Bret C
Synthetic miR-34a against solid tumours: a predictable failure.
Systemic impact of small regulatory RNAsMockly S, Seitz H
Chromatin-associated YTHDC1 coordinates heat-induced reprogramming of gene expression
Gene regulationKalina Timcheva, Solenne Dufour, Leila Touat-Todeschini, Callum Burnard, Marie-Christine Carpentier, Florent Chuffart, Rémy Merret, Marion Helsmoortel, Sabrina Ferré, Aude Grézy, Yohann Couté, Sophie Rousseau, Saadi Khochbin, Claire Vourc’h, Cécile Bousquet-Antonelli, Rosemary Kiernan, Daphné Seigneurin-Berny and André Verdel
Salvage therapy with brentuximab-vedotin and bendamustine for patients with R/R PTCL: a retrospective study from the LYSA.
Epigenome modifications and genomic instability in normal and malignant B cellsDamaj G, Aubrais R, Bouabdallah K, Chartier L, Herbaux C, Banos A, Brice P, Sibon D, Schiano JM, Cluzeau T, Laribi K, LE Calloch R, Bellal M, Delapierre B, Daguindau N, Amorim S, Agbetiafa K, Chauchet A, Besson C, Durot E, Bonnet C, Fouillet L, Bijou F, Tournilhac O, Gaulard P, Parrens MC
Programmed DNA elimination: New metazoan models.
Epigenetic Chromatin RegulationMochizuki K