Publications

Tubulin detyrosination shapes Leishmania cytoskeletal architecture and virulence.

Published the 14/01/2025 - Proc Natl Acad Sci U S A - pmid : 39808657 Tubulin code

Corrales RM, Vincent J, Crobu L, Neish R, Nepal B, Espeut J, Pasquier G, Gillard G, Cazevieille C, Mottram JC, Wetzel DM, Sterkers Y, Rogowski K, Lévêque MF

PIM2 inhibition promotes MCL1 dependency in plasma cells involving integrated stress response-driven NOXA expression.

Published the 03/01/2025 - Nat Commun - pmid : 39747141 Epigenome modifications and genomic instability in normal and malignant B cells

Haas M, Cherfa S, Nguyen L, Bourgoin M, Caron G, Dessauge E, Marchand T, Delpy L, Auberger P, Moreaux J, Jacquel A, Fest T

Synergistic effect of inhibiting CHK2 and DNA replication on cancer cell growth

Published the 30/12/2024 - eLife Maintenance of genome integrity during DNA replication

Flavie Coquel, Sing-Zong Ho, Keng-Chang Tsai, Chun-Yen Yang, Antoine Aze, Julie Devin, Ting-Hsiang Chang, Marie Kong-Hap, Audrey Bioteau, Jerome Moreaux, Domenico Maiorano, Philippe Pourquier, Wen-Chin Yang, Yea-Lih Lin, Philippe Pasero

more

Interchromosomal contacts between regulatory regions trigger stable transgenerational epigenetic inheritance in Drosophila.

Published the 13/12/2024 - Mol Cell - pmid : 39667935 Chromatin and cell biology

Fitz-James MH, Sabarís G, Sarkies P, Bantignies F, Cavalli G

read publication

more

TPR is required for cytoplasmic chromatin fragment formation during senescence

Published the 03/12/2024 - eLife - pmid : 39625470 Nuclear architecture in physiology and pathology

Bethany M Bartlett, Yatendra Kumar, Shelagh Boyle, Tamoghna Chowdhury, Andrea Quintanilla, Charlene Boumendil, Juan Carlos Acosta, Wendy A Bickmore

Evolution and function of chromatin domains across the tree of life.

Published the 27/11/2024 - Nat Struct Mol Biol - pmid : 39592879 Chromatin and cell biology

Szalay MF, Majchrzycka B, Jerković I, Cavalli G, Ibrahim DM

more

KDM6A controls immunogenicity in MM.

Published the 03/10/2024 - Blood - pmid : 39361299 Epigenome modifications and genomic instability in normal and malignant B cells

Moreaux J

Single-hit genome editing optimized for maturation in B cells redirects their specificity toward tumor antigens.

Published the 29/09/2024 - Sci Rep - pmid : 39342013 Epigenome modifications and genomic instability in normal and malignant B cells

Ueda N, Cahen M, Leonard J, Deleurme L, Dreano S, Sirac C, Galy A, Moreaux J, Danger Y, Cogné M

piRNAs are regulators of metabolic reprogramming in stem cells

Published the 27/09/2024 - Nature Communications - pmid : 39333531 mRNA Regulation and Development

Rojas-Ríos P, Chartier A, Enjolras C, Cremaschi J, Garret C, Boughlita A, Ramat A, Simonelig M

CD38, CD39, and BCL2 differentiate disseminated forms of high-grade B-cell lymphomas in biological fluids from Burkitt lymphoma and diffuse large B-cell lymphoma.

Published the 19/09/2024 - Cytometry B Clin Cytom - pmid : 39295433 Epigenome modifications and genomic instability in normal and malignant B cells

Marianini P, Lacheretz-Szablewski V, Almeras M, Moreaux J, Bret C

Spatial organization of translation and translational repression in two phases of germ granules

Published the 13/09/2024 - Nature Communications - pmid : 39271704 mRNA Regulation and Development

Anne Ramat, Ali Haidar, Céline Garret, Martine Simonelig

more

BHLHE41, a transcriptional repressor involved in physiological processes and tumor development.

Published the 10/09/2024 - Cell Oncol (Dordr) - pmid : 39254779 Epigenome modifications and genomic instability in normal and malignant B cells

Bret C, Desmots-Loyer F, Moreaux J, Fest T

A non-catalytic function for Rad18 in sustaining glioblastoma proliferation

Published the 10/09/2024 - BioRxiv Genome Surveillance and Stability

Chames Kermi, Nour Benbahouche, Lenka Stefancikova, Aurore Siegfried, Jean-Marc Pascussi, Julie Pannequin, Jérôme Moreaux, Tom Egger, Jean-Philippe Hugnot, Marie-Bernadette Delisle, Elizabeth Moyal, Emmanuelle Uro-Coste, Domenico Maiorano

more

A case of refractory IgG4-related disease successfully treated with daratumumab and lenalidomide.

Published the 24/08/2024 - Rheumatology (Oxford) - pmid : 39180414 Epigenome modifications and genomic instability in normal and malignant B cells

Coulomb D, Szablewski V, Robert N, Dupuy AM, Berrahouane R, Goulabchand R, Moreaux J, Maria ATJ, Herbaux C

FCGR3A F158V alleles frequency differs in multiple myeloma patients from healthy population.

Published the 23/08/2024 - Oncoimmunology - pmid : 39175948 Epigenome modifications and genomic instability in normal and malignant B cells

Constantinides M, Robert N, Multrier C, Coënon L, Campos-Mora M, Jacquard C, Gao F, Zemiti S, Presumey J, Cartron G, Moreaux J, Villalba M

A PRE loop at the dac locus acts as a topological chromatin structure that restricts and specifies enhancer-promoter communication.

Published the 17/08/2024 - Nat Struct Mol Biol - pmid : 39152239 Chromatin and cell biology

Denaud S, Bardou M, Papadopoulos GL, Grob S, Di Stefano M, Sabarís G, Nollmann M, Schuettengruber B, Cavalli G

read publication

more

A new perspective on microRNA-guided gene regulation specificity, and its potential generalization to transcription factors and RNA-binding proteins.

Published the 16/08/2024 - Nucleic Acids Res - pmid : 39149906 Systemic impact of small regulatory RNAs

Seitz H

more

FIGNL1-FIRRM is essential for meiotic recombination and prevents DNA damage-independent RAD51 and DMC1 loading

Published the 01/08/2024 - Nat Commun. - pmid : 39147779 Meiosis and recombination

Zainu, A., Dupaigne, P., Bouchouika, S., Cau, J., Clement, J.A.J., Auffret, P., Ropars, V., Charbonnier, J.B., de Massy, B., Mercier, R., Kumar, R. and Baudat, F.

more

The TOPOVIBL meiotic DSB formation protein: new insights from its biochemical and structural characterization

Published the 01/08/2024 - Nucleic Acids Res . - pmid : 38966985 Meiosis and recombination

Diagouraga, B., Tambones, I., Carivenc, C., Bechara, C., Nadal, M., de Massy, B., le Maire, A., and Robert, T.

more

Mapping Meiotic DNA Breaks: Two Fully-Automated Pipelines to Analyze Single-Strand DNA Sequencing Data, hotSSDS and hotSSDS-extra

Published the 01/08/2024 - Methods Mol Biol. - pmid : 38351457 Meiosis and recombination

Auffret, P., de Massy, B., and Clement, J.A.J.

more

Publications

Search filter