Publications
Emerging roles and functional mechanisms of PIWI-interacting RNAs.
mRNA Regulation and DevelopmentWang X, Ramat A, Simonelig M, Liu MF
Alternative pathways driven by STING: From innate Immunity to lipid metabolism.
Molecular Basis of InflammationVila IK, Guha S, Kalucka J, Olagnier D, Laguette N.
Integrative Analysis Reveals Histone Demethylase LSD1 Promotes RNA Polymerase II Pausing
Biology of distal regulatory elementsKim HJ, Li P, Kim T, Oldfield AJ, Zheng X, Yang P.
Activating translation with phase separation
mRNA Regulation and DevelopmentAnne Ramat and Martine Simonelig
TRIM28-dependent SUMOylation protects the adult ovary from activation of the testicular pathway
Development and Pathology of the gonadMoïra Rossitto , Stephanie Déjardin , Chris M Rands , Stephanie Le Gras , Roberta Migale , Mahmoud-Reza Rafiee , Yasmine Neirijnck , Alain Pruvost , Anvi Laetitia Nguyen , Guillaume Bossis , Florence Cammas , Lionel Le Gallic , Dagmar Wilhelm , Robin Lovell-Badge , Brigitte Boizet-Bonhoure , Serge Nef , Francis Poulat
Angiotensin II induces reactive oxygen species, DNA damage, and T cell apoptosis in severe COVID-19.
Homing, immune activation and infectionKundura L, Gimenez S, Cezar R, André S, Younas M, Lin YL, Portales P, Lozano C, Boulle C, Reynes J, Thierry V, Mettling C, Pasero P, Muller L, Lefrant JY, Roger C, Claret PG, Duvnjak S, Loubet P, Sotto A, Tran TA, Estaquier J, Corbeau P
The crosstalk between DNA-PK and cGAS drives tumor immunogenicity
Molecular Basis of InflammationClara Taffoni, Johanna Marines, Hanane Chamma, Mathilde Saccas, Amel Bouzid, Soumyabrata Guha, Ana-Luiza Chaves Valadao, Katarzyna Polak, Maguy Del Rio, Celine Gongora, Donovan Pineau, Jean-Philippe Hugnot, Karima Kissa, Laura Fontenille, Fabien P. Blanchet, Isabelle K. Vila, Nadine Laguette
RNF219 regulates CCR4-NOT function in mRNA translation and deadenylation
Laboratory of Molecular VirologyAude Guénolé, Fabien Velilla, Aymeric Chartier, April Rich, Anne-Ruxandra Carvunis, Claude Sardet, Martine Simonelig & Bijan Sobhian
Protocol to induce and assess cGAS-STING pathway activation in vitro.
Molecular Basis of InflammationChamma H, Guha S, Laguette N, Vila IK
A rationalized definition of general tumor suppressor microRNAs excludes miR-34a
Systemic impact of small regulatory RNAsSophie Mockly, Élisabeth Houbron, Hervé Seitz
Activation of STING in the pancreatic tumor microenvironment: A novel therapeutic opportunity
Molecular Basis of InflammationHanane Chamma, Isabelle K Vila, Clara Taffoni, Andrei Turtoi, Nadine Laguette
The Drosophila chemokine-like Orion bridges phosphatidylserine and Draper in phagocytosis of neurons
Neurogenetics and memoryHui Ji, Bei Wang, David Labib, Joyce Lei, Xinchen Chen, Maria Sapar, Ana Boulanger, Jean-Maurice Dura, Chun Han
A shared ancient enhancer element differentially regulates the bric-a-brac tandem gene duplicates in the developing Drosophila leg.
Chromatin and cell biologyBourbon HG, Benetah MH, Guillou E, Mojica-Vazquez LH, Baanannou A, Bernat-Fabre S, Loubiere V, Bantignies F, Cavalli G, Boube M
Using Experimental Models to Decipher the Effects of Acetaminophen and NSAIDs on Reproductive Development and Health
Development and Pathology of the gonadB. Boizet-Bonhoure, S. Dejardin, M. Rossitto, F. Poulat and P. Philibert
Comprehensive characterization of the epigenetic landscape in Multiple Myeloma.
Chromatin and cell biologyAlaterre E, Ovejero S, Herviou L, de Boussac H, Papadopoulos G, Kulis M, Boireau S, Robert N, Requirand G, Bruyer A, Cartron G, Vincent L, Martinez AM, Martin-Subero JI, Cavalli G, Moreaux J
SETDB1/NSD-dependent H3K9me3/H3K36me3 dual heterochromatin maintains gene expression profiles by bookmarking poised enhancers.
Biology of distal regulatory elementsBarral A, Pozo G, Ducrot L, Papadopoulos GL, Sauzet S, Oldfield AJ, Cavalli G, Déjardin J.
Histone marks are drivers of the splicing changes necessary for an epithelial-to-mesenchymal transition
Chromatin and SplicingAlexandre Segelle, Yaiza Nunez-Alvarez, Andrew J Oldfield, Kimberly M Webb, Philipp Voigt, Reini F Luco
Histone marks regulate the epithelial-to-mesenchymal transition via alternative splicing.
Biology of distal regulatory elementsSegelle A, Núñez-Álvarez Y, Oldfield AJ, Webb KM, Voigt P, Luco RF.