Mitosis without DNA replication in mammalian somatic cells
Replication and Genome DynamicsGanier O, Lutzmann M, Cau, J, Peiffer I., Lemmers C, Zitouni S, Theillet C, and Méchali, M
Publications
The Mi-2 nucleosome remodeler and the Rpd3 histone deacetylase are involved in piRNA-guided heterochromatin formation
Non-coding RNA, epigenetics and genome stabilityBruno Mugat, Simon Nicot, Carolina Varela-Chavez, Christophe Jourdan, Kaoru Sato, Eugenia Basyuk, François Juge, Mikiko C. Siomi, Alain Pélisson & Séverine Chambeyron
Lysyl-tRNA synthetase produces diadenosine tetraphosphate to curb STING-dependent inflammation
Molecular Basis of InflammationJ. Guerra, A.-L. Valadao, D. Vlachakis, K. Polak, I. K. Vila, C. Taffoni, T. Prabakaran, A. S. Marriott, R. Kaczmarek, A. Houel, B. Auzemery,S. Déjardin,P. Boudinot, B. Nawrot, N. J. Jones, S. R. Paludan, S. Kossida, C. Langevin and N. Laguette
A localization screen reveals translation factories and widespread co-translational protein targeting.
Cell Biology of RNAChouaib, R., Safieddine, A., Pichon, X., Kwon, OS., Samacoits, A., Traboulsi, AM., Tsanov, N., Robert, MC., Coleno, E., Poser, I., Zimmer, C., Hyman, A. A., Le Hir, H., Zibara, K., Peter, M., Mueller, F.*, Walter, T.*, and E. Bertrand* *. co-corresponding authors.
NF90 modulates processing of a subset of human pri-miRNAs
Gene regulationGrasso G, Higuchi T, Mac V, Barbier J, Helsmoortel M, Lorenzo C, Sanchez G, Bello M, Ritchie W, Sakamoto S, and Kiernan R.
Homologous recombination and Mus81 promote replication completion in response to replication fork blockage
Maintenance of genome integrity during DNA replicationBenjamin Pardo, María Moriel‐Carretero, Thibaud Vicat, Andrés Aguilera and Philippe Pasero
Characterization of immortalized human islet stromal cells reveals a MSC-like profile with pancreatic features.
Epigenome modifications and genomic instability in normal and malignant B cellsVillard O, Armanet M, Couderc G, Bony C, Moreaux J, Noel D, De Vos J, Klein B, Veyrune JL, Wojtusciszyn A
Live-cell imaging reveals the spatiotemporal organization of endogenous RNA polymerase II phosphorylation at a single gene.
Cell Biology of RNAForero-Quintero, L. S., Raymond, W., Handa, T., Saxton, M., Morisaki, T., Kimura, H., Bertrand, E., Munsky, B. and T. J. Stasevich
4D Genome Rewiring during Oncogene-Induced and Replicative Senescence
Chromatin and cell biologySati, S., Bonev, B., Szabo, Q., Jost, D., Bensadoun, P., Serra, F., Loubiere...
Exploring histone loading on HIV DNA reveals a dynamic nucleosome positioning between unintegrated and integrated viral genome.
Laboratory of Molecular VirologyMachida S, Depierre D, Chen HC, Thenin-Houssier S, Petitjean G, Doyen CM, Takaku M, Cuvier O, Benkirane M
Mec1 Is Activated at the Onset of Normal S Phase by Low-dNTP Pools Impeding DNA Replication
Maintenance of genome integrity during DNA replicationRomain Forey, Ana Poveda, Sushma Sharma, Antoine Barthe, Ismael Padioleau, Claire Renard, Robin Lambert, Magdalena Skrzypczak, Krzysztof Ginalski, Armelle Lengronne, Andrei Chabes, Benjamin Pardo, Philippe Pasero
Telomeric Chromatin and TERRA.
Biology of Repetitive SequencesBarral A, Déjardin J
Purification and enrichment of specific chromatin loci.
Biology of Repetitive SequencesGauchier M, van Mierlo G, Vermeulen M, Déjardin J
The PIWI protein Aubergine recruits eIF3 to activate translation in the germ plasm
mRNA Regulation and DevelopmentAnne Ramat, Maria-Rosa Garcia-Silva, Camille Jahan, Rima Naït-Saïdi, Jérémy Dufourt, Céline Garret, Aymeric Chartier, Julie Cremaschi, Vipul Patel, Mathilde Decourcelle, Amandine Bastide, François Juge & Martine Simonelig
Kinome expression profiling to target new therapeutic avenues in multiple myeloma
Epigenome modifications and genomic instability in normal and malignant B cellsHugues de Boussac Angélique Bruyer Michel Jourdan Anke Maes Nicolas Robert Claire Gourzones Laure Vincent Anja Seckinger Guillaume Cartron Dirk Hose Elke De Bruyne Alboukadel Kassambara Philippe Pasero Jérôme Moreaux
Transcriptional network dynamics during the progression of pluripotency revealed by integrative statistical learning.
Biology of distal regulatory elementsKim HJ, Osteil P, Humphrey SJ, Cinghu S, Oldfield AJ, Patrick E, Wilkie EE, Peng G, Suo S, Jothi R, Tam PPL, Yang P.
Dihydropyrimidinase protects from DNA replication stress caused by cytotoxic metabolites
Genome Surveillance and StabilityJihane Basbous, Antoine Aze, Laurent Chaloin, Rana Lebdy, Dana Hodroj, Cyril Ribeyre, Marion Larroque, Caitlin Shepard, Baek Kim, Alain Pruvost, Jérôme Moreaux, Domenico Maiorano, Marcel Mechali, Angelos Constantinou
Control of cell shape during epithelial morphogenesis: recent advances.
Tubulin codeGillard G, Röper K
Prospects and challenges of multi-omics data integration in toxicology.
Systemic impact of small regulatory RNAsCanzler S, Schor J, Busch W, Schubert K, Rolle-Kampczyk UE, Seitz H, Kamp H, von Bergen M, Buesen R, Hackermüller J