SETDB1/NSD-dependent H3K9me3/H3K36me3 dual heterochromatin maintains gene expression profiles by bookmarking poised enhancers.
Chromatin and cell biologyBarral A, Pozo G, Ducrot L, Papadopoulos GL, Sauzet S, Oldfield AJ, Cavalli G, Déjardin J
Publications
NF90 Interacts with Components of RISC and Modulates Association of Ago2 with mRNA
Gene regulationGiuseppa Grasso, Charbel Akkawi, Celine Franckhauser, Rima Nait-Saidi, Maxime Bello, Jérôme Barbier, Rosemary Kiernan
Translesion DNA synthesis-driven mutagenesis in very early embryogenesis of fast cleaving embryos
Genome Surveillance and StabilityLo Furno E., Busseau I., Aze A., Lorenzi C., Saghira C., Danzi M., Zuchner S., Maiorano D.
Four-pronged negative feedback of DSB machinery in meiotic DNA-break control in mice
Meiosis and recombinationIhsan Dereli, Marcello Stanzione, Fabrizio Olmeda, Frantzeskos Papanikos, Marek Baumann, Sevgican Demir, Fabrizia Carofiglio, Julian Lange, Bernard de Massy, Willy M Baarends, James Turner, Steffen Rulands, Attila Tóth
Mechanisms of Polycomb group protein function in cancer.
Chromatin and cell biologyParreno V, Martinez AM, Cavalli G
Activation of the ubiquitin-proteasome system contributes to oculopharyngeal muscular dystrophy through muscle atrophy.
mRNA Regulation and DevelopmentRibot C, Soler C, Chartier A, Al Hayek S, Naït-Saîdi R, Barbezier N, Coux O, Simonelig M
Molecular mechanisms of transgenerational epigenetic inheritance.
Chromatin and cell biologyFitz-James MH, Cavalli G
STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses
Isabelle K.Vila, Hanane Chamma, Alizée Steer, Mathilde Saccas, Clara Taffoni, Evgenia Turtoi, Line S.Reinert, Saqib Hussain, Johanna Marines, Lei Jin, Xavier Bonnefont, Mathieu Hubert, Olivier Schwartz, Soren R.Paludan, Gaetan Van Simaeys, Gilles Doumont, Bijan Sobhian, Dimitrios Vlachakis, Andrei Turtoi, Nadine Laguette
IMGT® databases, related tools and web resources through three main axes of research and development.
IMGT® - the international ImMunoGeneTics information system®Manso T, Folch G, Giudicelli V, Jabado-Michaloud J, Kushwaha A, Nguefack Ngoune V, Georga M, Papadaki A, Debbagh C, Pégorier P, Bertignac M, Hadi-Saljoqi S, Chentli I, Cherouali K, Aouinti S, El Hamwi A, Albani A, Elazami Elhassani M, Viart B, Goret A, Tran A, Sanou G, Rollin M, Duroux P, Kossida S
Angiogenic factors could help us to define patients obtaining complete response with undetectable minimal residual disease in untreated CLL patients treated by FCR: results from the CLL2010FMP, a FILO study.
Epigenome modifications and genomic instability in normal and malignant B cellsGagez AL, Paul F, Alaterre E, Gouilleux-Gruart V, Tuaillon E, Lepretre S, Ternant D, Letestu R, Moreaux J, Cartron G
Studying the DNA damage response in embryonic systems.
Genome Surveillance and StabilityLo Furno E, Recolin B, van der Laan S, Aze A, Maiorano D
IRFinder-S: a comprehensive suite to discover and explore intron retention.
Biology of distal regulatory elementsLorenzi C, Barriere S, Arnold K, Luco RF, Oldfield AJ, Ritchie W.
Editorial: Nucleic Acid-Associated Inflammation.
Laguette N, Langevin C, Olagnier D, Torraca V, Vanpouille-Box C, Verrier ER.
RNA-Sequencing-Based Transcriptomic Score with Prognostic and Theranostic Values in Multiple Myeloma.
Epigenome modifications and genomic instability in normal and malignant B cellsAlaterre E, Vikova V, Kassambara A, Bruyer A, Robert N, Requirand G, Bret C, Herbaux C, Vincent L, Cartron G, Elemento O, Moreaux J
Decoding the function of bivalent chromatin in development and cancer.
Biology of distal regulatory elementsKumar D, Cinghu S, Oldfield AJ, Yang P, Jothi R.
Ibrutinib Plus Rituximab Versus Placebo Plus Rituximab for Waldenström's Macroglobulinemia: Final Analysis From the Randomized Phase III iNNOVATE Study.
Epigenome modifications and genomic instability in normal and malignant B cellsBuske C, Tedeschi A, Trotman J, García-Sanz R, MacDonald D, Leblond V, Mahe B, Herbaux C, Matous JV, Tam CS, Heffner LT, Varettoni M, Palomba ML, Shustik C, Kastritis E, Treon SP, Ping J, Hauns B, Arango-Hisijara I, Dimopoulos MA
A regulatory phosphorylation site on Mec1 controls chromatin occupancy of RNA polymerases during replication stress.
Maintenance of genome integrity during DNA replicationHurst V, Challa K, Jonas F, Forey R, Sack R, Seebacher J, Schmid CD, Barkai N, Shimada K, Gasser SM, Poli J
Targeting the methyltransferase SETD8 impairs tumor cell survival and overcomes drug resistance independently of p53 status in multiple myeloma.
Epigenome modifications and genomic instability in normal and malignant B cellsHerviou L, Ovejero S, Izard F, Karmous-Gadacha O, Gourzones C, Bellanger C, De Smedt E, Ma A, Vincent L, Cartron G, Jin J, De Bruyne E, Grimaud C, Julien E, Moreaux J
The microenvironment of DLBCL is characterized by noncanonical macrophages recruited by tumor-derived CCL5.
Epigenome modifications and genomic instability in normal and malignant B cellsManfroi B, De Grandis M, Moreaux J, Tabruyn S, Mayol JF, Quintero M, Righini C, Sturm N, Aurrand-Lions M, Huard B