Publications

Cornelia de Lange syndrome-associated mutations cause a DNA damage signalling and repair defect

Published the 25/05/2021 - Nature Communications Nuclear architecture in physiology and pathology

Gabrielle Olley, Madapura M. Pradeepa, Graeme R. Grimes, Sandra Piquet, Sophie E. Polo, David R. FitzPatrick, Wendy A. Bickmore, Charlene Boumendil

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Chromatin-associated MRN complex protects highly transcribing genes from genomic instability

Published the 21/05/2021 - Science Advances Gene regulation

Kader Salifou, Callum Burnard, Poornima Basavarajaiah, Marion Helsmoortel, Victor Mac, David Depierre, Giuseppa Grasso, Céline Franckhauser, Emmanuelle Beyne, Xavier Contreras, Jérôme Dejardin, Sylvie Rouquier, Olivier Cuvier, Rosemary Kiernan

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Nucleic Acid Immunity and DNA Damage Response: New Friends and Old Foes.

Published the 14/05/2021 - Front Immunol - pmid : 33981307

Taffoni C, Steer A, Marines J, Chamma H, Vila IK, Laguette N

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Discovery of candidate DNA methylation cancer driver genes.

Published the 10/05/2021 - Cancer Discov - pmid : 33972312 Epigenome modifications and genomic instability in normal and malignant B cells

Pan H, Renaud L, Chaligne R, Bloehdorn J, Tausch E, Mertens D, Fink AM, Fischer K, Zhang C, Betel D, Gnirke A, Imielinski M, Moreaux J, Hallek M, Meissner A, Stilgenbauer S, Wu CJ, Elemento O, Landau DA

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Obinutuzumab and idelalisib in symptomatic patients with relapsed/refractory Waldenström macroglobulinemia.

Published the 08/05/2021 - Blood Adv - pmid : 33961019 Epigenome modifications and genomic instability in normal and malignant B cells

Tomowiak C, Poulain S, Herbaux C, Perrot A, Mahé B, Morel P, Aurran T, Tournilhac O, Leprêtre S, Assaad S, Villemagne B, Casasnovas O, Nollet D, Roos-Weil D, Chevret S, Leblond V

Understanding 3D genome organization by multidisciplinary methods

Published the 05/05/2021 - Nature Reviews Molecular Cell Biology Chromatin and cell biology

Ivana Jerkovic´ & Giacomo Cavalli

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In the mouse, prostaglandin D2 signalling protects the endometrium against adenomyosis

Published the 05/05/2021 - Molecular Human reproduction - pmid : 33851217 Development and Pathology of the gonad

Pascal Philibert, Stéphanie Déjardin, Nelly Pirot, Alain Pruvost, Anvi Laetitia Nguyen, Florence Bernex, Francis Poulat, Brigitte Boizet-Bonhoure

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G9a/GLP targeting in MM promotes autophagy-associated apoptosis and boosts proteasome inhibitor-mediated cell death.

Published the 04/05/2021 - Blood Adv - pmid : 33938943 Epigenome modifications and genomic instability in normal and malignant B cells

De Smedt E, Devin J, Muylaert C, Robert N, Requirand G, Vlummens P, Vincent L, Cartron G, Maes K, Moreaux J, De Bruyne E

A cell-to-patient machine learning transfer approach uncovers novel basal-like breast cancer prognostic markers amongst alternative splice variants.

Published the 12/04/2021 - BMC Biol. - pmid : 33845831 Biology of distal regulatory elements

Villemin JP, Lorenzi C, Cabrillac MS, Oldfield A, Ritchie W, Luco RF.

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A cell-to-patient machine learning transfer approach uncovers novel basal-like breast cancer prognostic markers amongst alternative splice variants

Published the 12/04/2021 - BMC Biology

Jean-Philippe Villemin, Claudio Lorenzi, Marie-Sarah Cabrillac, Andrew Oldfield, William Ritchie & Reini F. Luco

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Translesion Synthesis or Repair by Specialized DNA Polymerases Limits Excessive Genomic Instability upon Replication Stress.

Published the 10/04/2021 - Int J Mol Sci - pmid : 33920223 Genome Surveillance and Stability

Maiorano D, El Etri J, Franchet C, Hoffmann JS

RNA-sequencing data-driven dissection of human plasma cell differentiation reveals new potential transcription regulators.

Published the 08/04/2021 - Leukemia - pmid : 33824465 Epigenome modifications and genomic instability in normal and malignant B cells

Kassambara A, Herviou L, Ovejero S, Jourdan M, Thibaut C, Vikova V, Pasero P, Elemento O, Moreaux J

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Immunotherapy perspectives in the new era of B-cell editing.

Published the 24/03/2021 - Blood Adv - pmid : 33755093 Epigenome modifications and genomic instability in normal and malignant B cells

Ueda N, Cahen M, Danger Y, Moreaux J, Sirac C, Cogné M

Axonal chemokine-like Orion induces astrocyte infiltration and engulfment during mushroom body neuronal remodeling

Published the 23/03/2021 - Nature Communications Neurogenetics and memory

Ana Boulanger, Camille Thinat, Stephan Züchner, Lee G. Fradkin, Hugues Lortat-Jacob, Jean-Maurice Dura

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TopBP1 assembles nuclear condensates to switch on ATR signaling.

Published the 18/03/2021 - Molecular Cell. - pmid : 33503405 Genetic Instability and Cancer

Frattini C, Promonet A, Alghoul E, Vidal-Eychenie S, Lamarque M, Blanchard MP, Urbach S, Basbous J, Constantinou A

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The origin of preplasmablastic cells.

Published the 04/03/2021 - Blood - pmid : 33661294 Epigenome modifications and genomic instability in normal and malignant B cells

Moreaux J

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Exon junction complex dependent mRNA localization is linked to centrosome organization during ciliogenesis

Published the 01/03/2021 - Nature Communications Cell Biology of RNA

Oh Sung Kwon, Rahul Mishra, Adham Safieddine, Emeline Coleno, Quentin Alasseur, Marion Faucourt, Isabelle Barbosa, Edouard Bertrand, Nathalie Spassky, Hervé Le Hir

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A choreography of centrosomal mRNAs reveals a conserved localization mechanism involving active polysome transport

Published the 01/03/2021 - Nature Communications Cell Biology of RNA

Adham Safieddine, Emeline Coleno, Soha Salloum, Arthur Imbert, Abdel-Meneem Traboulsi, Oh Sung Kwon, Frederic Lionneton, Virginie Georget, Marie-Cécile Robert, Thierry Gostan, Charles-Henri Lecellier, Racha Chouaib, Xavier Pichon, Hervé Le Hir, Kazem Zibara, Florian Mueller, Thomas Walter, Marion Peter, Edouard Bertrand

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