Nucleic Acid Immunity and DNA Damage Response: New Friends and Old Foes.
Taffoni C, Steer A, Marines J, Chamma H, Vila IK, Laguette N
Publications
Discovery of candidate DNA methylation cancer driver genes.
Epigenome modifications and genomic instability in normal and malignant B cellsPan H, Renaud L, Chaligne R, Bloehdorn J, Tausch E, Mertens D, Fink AM, Fischer K, Zhang C, Betel D, Gnirke A, Imielinski M, Moreaux J, Hallek M, Meissner A, Stilgenbauer S, Wu CJ, Elemento O, Landau DA
Obinutuzumab and idelalisib in symptomatic patients with relapsed/refractory Waldenström macroglobulinemia.
Epigenome modifications and genomic instability in normal and malignant B cellsTomowiak C, Poulain S, Herbaux C, Perrot A, Mahé B, Morel P, Aurran T, Tournilhac O, Leprêtre S, Assaad S, Villemagne B, Casasnovas O, Nollet D, Roos-Weil D, Chevret S, Leblond V
Understanding 3D genome organization by multidisciplinary methods
Chromatin and cell biologyIvana Jerkovic´ & Giacomo Cavalli
In the mouse, prostaglandin D2 signalling protects the endometrium against adenomyosis
Development and Pathology of the gonadPascal Philibert, Stéphanie Déjardin, Nelly Pirot, Alain Pruvost, Anvi Laetitia Nguyen, Florence Bernex, Francis Poulat, Brigitte Boizet-Bonhoure
G9a/GLP targeting in MM promotes autophagy-associated apoptosis and boosts proteasome inhibitor-mediated cell death.
Epigenome modifications and genomic instability in normal and malignant B cellsDe Smedt E, Devin J, Muylaert C, Robert N, Requirand G, Vlummens P, Vincent L, Cartron G, Maes K, Moreaux J, De Bruyne E
A cell-to-patient machine learning transfer approach uncovers novel basal-like breast cancer prognostic markers amongst alternative splice variants.
Biology of distal regulatory elementsVillemin JP, Lorenzi C, Cabrillac MS, Oldfield A, Ritchie W, Luco RF.
A cell-to-patient machine learning transfer approach uncovers novel basal-like breast cancer prognostic markers amongst alternative splice variants
Jean-Philippe Villemin, Claudio Lorenzi, Marie-Sarah Cabrillac, Andrew Oldfield, William Ritchie & Reini F. Luco
Translesion Synthesis or Repair by Specialized DNA Polymerases Limits Excessive Genomic Instability upon Replication Stress.
Genome Surveillance and StabilityMaiorano D, El Etri J, Franchet C, Hoffmann JS
RNA-sequencing data-driven dissection of human plasma cell differentiation reveals new potential transcription regulators.
Epigenome modifications and genomic instability in normal and malignant B cellsKassambara A, Herviou L, Ovejero S, Jourdan M, Thibaut C, Vikova V, Pasero P, Elemento O, Moreaux J
Immunotherapy perspectives in the new era of B-cell editing.
Epigenome modifications and genomic instability in normal and malignant B cellsUeda N, Cahen M, Danger Y, Moreaux J, Sirac C, Cogné M
Axonal chemokine-like Orion induces astrocyte infiltration and engulfment during mushroom body neuronal remodeling
Neurogenetics and memoryAna Boulanger, Camille Thinat, Stephan Züchner, Lee G. Fradkin, Hugues Lortat-Jacob, Jean-Maurice Dura
TopBP1 assembles nuclear condensates to switch on ATR signaling.
Genetic Instability and CancerFrattini C, Promonet A, Alghoul E, Vidal-Eychenie S, Lamarque M, Blanchard MP, Urbach S, Basbous J, Constantinou A
Exon junction complex dependent mRNA localization is linked to centrosome organization during ciliogenesis
Cell Biology of RNAOh Sung Kwon, Rahul Mishra, Adham Safieddine, Emeline Coleno, Quentin Alasseur, Marion Faucourt, Isabelle Barbosa, Edouard Bertrand, Nathalie Spassky, Hervé Le Hir
A choreography of centrosomal mRNAs reveals a conserved localization mechanism involving active polysome transport
Cell Biology of RNAAdham Safieddine, Emeline Coleno, Soha Salloum, Arthur Imbert, Abdel-Meneem Traboulsi, Oh Sung Kwon, Frederic Lionneton, Virginie Georget, Marie-Cécile Robert, Thierry Gostan, Charles-Henri Lecellier, Racha Chouaib, Xavier Pichon, Hervé Le Hir, Kazem Zibara, Florian Mueller, Thomas Walter, Marion Peter, Edouard Bertrand
Regulation of the conserved 3'-5' exoribonuclease EXOSC10/Rrp6 during cell division, development and cancer.
Stuparević I, Novačić A, Rahmouni AR, Fernandez A, Lamb N, Primig M
Splicing-associated chromatin signatures: a combinatorial and position-dependent role for histone marks in splicing definition.
Agirre E, Oldfield AJ, Bellora N, Segelle A, Luco RF
Anti-prion Drugs Targeting the Protein Folding Activity of the Ribosome Reduce PABPN1 Aggregation.
mRNA Regulation and DevelopmentBamia A, Sinane M, Naït-Saïdi R, Dhiab J, Keruzoré M, Nguyen PH, Bertho A, Soubigou F, Halliez S, Blondel M, Trollet C, Simonelig M, Friocourt G, Béringue V, Bihel F, Voisset C