Publications

PRC2 targeting is a therapeutic strategy for EZ score defined high-risk multiple myeloma patients and overcome resistance to IMiDs

Published the 03/10/2018 - Clinical Epigenetics Epigenome modifications and genomic instability in normal and malignant B cells

Laurie Herviou, Alboukadel Kassambara, Stéphanie Boireau, Nicolas Robert, Guilhem Requirand, Carsten Müller-Tidow, Laure Vincent, Anja Seckinger, Hartmut Goldschmidt, Guillaume Cartron, Dirk Hose, Giacomo Cavalli & Jerome Moreaux

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Challenges and guidelines toward 4D nucleome data and model standards.

Published the 29/09/2018 - Nat Genet - pmid : 30262815 Chromatin and cell biology

Marti-Renom MA, Almouzni G, Bickmore WA, Bystricky K, Cavalli G, Fraser P, Gasser SM, Giorgetti L, Heard E, Nicodemi M, Nollmann M, Orozco M, Pombo A, Torres-Padilla ME

Loss of PRC1 induces higher-order opening of Hox loci independently of transcription during Drosophila embryogenesis.

Published the 27/09/2018 - Nat Commun - pmid : 30254245 Chromatin and cell biology

Cheutin T, Cavalli G

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Descours et al. reply.

Published the 21/09/2018 - Nature - pmid : 30232426 Laboratory of Molecular Virology

Descours B, Petitjean G, Benkirane M

Recent advances in understanding DNA replication: cell type-specific adaptation of the DNA replication program.

Published the 20/09/2018 - F1000Res - pmid : 30228862 Genome Surveillance and Stability

+ Replication and Genome Dynamics

Aze A, Maiorano D

Use of IMGT® Databases and Tools for Antibody Engineering and Humanization.

Published the 10/09/2018 - Methods Mol Biol - pmid : 30196491 IMGT® - the international ImMunoGeneTics information system®

Lefranc MP, Ehrenmann F, Kossida S, Giudicelli V, Duroux P

piRNAs and PIWI proteins: regulators of gene expression in development and stem cells.

Published the 09/09/2018 - Development - pmid : 30194260 mRNA Regulation and Development

Rojas-Ríos P, Simonelig M

Mrc1 and Rad9 cooperate to regulate initiation and elongation of DNA replication in response to DNA damage.

Published the 31/08/2018 - EMBO J - pmid : 30158111 Maintenance of genome integrity during DNA replication

Bacal J, Moriel-Carretero M, Pardo B, Barthe A, Sharma S, Chabes A, Lengronne A, Pasero P

PRDM9, a driver of the genetic map.

Published the 31/08/2018 - PLoS Genet - pmid : 30161134 Meiosis and recombination

Grey C, Baudat F, de Massy B

DDK Has a Primary Role in Processing Stalled Replication Forks to Initiate Downstream Checkpoint Signaling.

Published the 30/08/2018 - Neoplasia - pmid : 30157471 Maintenance of genome integrity during DNA replication

Sasi NK, Coquel F, Lin YL, MacKeigan JP, Pasero P, Weinreich M

Physiological and druggable skipping of immunoglobulin variable exons in plasma cells.

Published the 22/08/2018 - Cell Mol Immunol - pmid : 30127381 Maintenance of genome integrity during DNA replication

Ashi MO, Srour N, Lambert JM, Marchalot A, Martin O, Le Noir S, Pinaud E, Ayala MV, Sirac C, Saulière J, Moreaux J, Cogné M, Delpy L

[EZH2 is therapeutic target for personalized treatment in multiple myeloma].

Published the 26/07/2018 - Bull Cancer - pmid : 30041976 Maintenance of genome integrity during DNA replication

+ Chromatin and cell biology

Herviou L, Cavalli G, Moreaux J

Polycomb-Dependent Chromatin Looping Contributes to Gene Silencing during Drosophila Development.

Published the 17/07/2018 - Mol Cell - pmid : 30008320 Chromatin and cell biology

Ogiyama Y, Schuettengruber B, Papadopoulos GL, Chang JM, Cavalli G

Tumor-associated neutrophils correlate with poor prognosis in diffuse large B-cell lymphoma patients.

Published the 07/07/2018 - Blood Cancer J - pmid : 29977076 Epigenome modifications and genomic instability in normal and malignant B cells

Manfroi B, Moreaux J, Righini C, Ghiringhelli F, Sturm N, Huard B

Intergenerational effects on mouse sperm quality after in utero exposure to acetaminophen and ibuprofen.

Published the 07/07/2018 - FASEB J - pmid : 29979629 Development and Pathology of the gonad

Rossitto M, Marchive C, Pruvost A, Sellem E, Ghettas A, Badiou S, Sutra T, Poulat F, Philibert P, Boizet-Bonhoure B

XPC is an RNA polymerase II cofactor recruiting ATAC to promoters by interacting with E2F1.

Published the 06/07/2018 - Nat Commun - pmid : 29973595 Laboratory of Molecular Virology

Bidon B, Iltis I, Semer M, Nagy Z, Larnicol A, Cribier A, Benkirane M, Coin F, Egly JM, Le May N

Exploring the Roles of CREBRF and TRIM2 in the Regulation of Angiogenesis by High-Density Lipoproteins.

Published the 01/07/2018 - Int J Mol Sci - pmid : 29958463 Machine learning and gene regulation

Wong NKP, Cheung H, Solly EL, Vanags LZ, Ritchie W, Nicholls SJ, Ng MKC, Bursill CA, Tan JTM

Sex reversal following deletion of a single distal enhancer of Sox9.

Published the 16/06/2018 - Science - pmid : 29903884 Development and Pathology of the gonad

Gonen N, Futtner CR, Wood S, Garcia-Moreno SA, Salamone IM, Samson SC, Sekido R, Poulat F, Maatouk DM, Lovell-Badge R

Small RNA-Mediated trans-Nuclear and trans-Element Communications in Tetrahymena DNA Elimination.

Published the 12/06/2018 - Curr Biol - pmid : 29887308 Epigenetic Chromatin Regulation

Noto T, Mochizuki K

Analysis of Global Gene Expression Profiles.

Published the 26/05/2018 - Methods Mol Biol - pmid : 29797258 Epigenome modifications and genomic instability in normal and malignant B cells

Kassambara A, Moreaux J