Publications

Increased Neutrophil Surface PD-L1 Expression in Tobacco Smokers: Consequences for Anti-PD-1 Treatment.

Homing, immune activation and infection

Psomas C, Tuaillon E, Marin G, Reynes J, Corbeau P

i-BLESS is an ultra-sensitive method for detection of DNA double-strand breaks.

Maintenance of genome integrity during DNA replication

Biernacka A, Zhu Y, Skrzypczak M, Forey R, Pardo B, Grzelak M, Nde J, Mitra A, Kudlicki A, Crosetto N, Pasero P, Rowicka M, Ginalski K

The Mouse Microbiome Is Required for Sex-Specific Diurnal Rhythms of Gene Expression and Metabolism.

Development and Pathology of the gonad

Weger BD, Gobet C, Yeung J, Martin E, Jimenez S, Betrisey B, Foata F, Berger B, Balvay A, Foussier A, Charpagne A, Boizet-Bonhoure B, Chou CJ, Naef F, Gachon F

Microtubule polyglutamylation and acetylation drive microtubule dynamics critical for platelet formation.

Development and Pathology of the gonad

+ Tubulin code

van Dijk J, Bompard G, Cau J, Kunishima S, Rabeharivelo G, Mateos-Langerak J, Cazevieille C, Cavelier P, Boizet-Bonhoure B, Delsert C, Morin N

The somatic piRNA pathway controls germline transposition over generations.

Non-coding RNA, epigenetics and genome stability

Barckmann B, El-Barouk M, Pélisson A, Mugat B, Li B, Franckhauser C, Fiston Lavier AS, Mirouze M, Fablet M, Chambeyron S

PRC2 targeting is a therapeutic strategy for EZ score defined high-risk multiple myeloma patients and overcome resistance to IMiDs.

Maintenance of genome integrity during DNA replication

+ Chromatin and cell biology

Herviou L, Kassambara A, Boireau S, Robert N, Requirand G, Müller-Tidow C, Vincent L, Seckinger A, Goldschmidt H, Cartron G, Hose D, Cavalli G, Moreaux J

PRC2 targeting is a therapeutic strategy for EZ score defined high-risk multiple myeloma patients and overcome resistance to IMiDs

Epigenome modifications and genomic instability in normal and malignant B cells

Laurie Herviou, Alboukadel Kassambara, Stéphanie Boireau, Nicolas Robert, Guilhem Requirand, Carsten Müller-Tidow, Laure Vincent, Anja Seckinger, Hartmut Goldschmidt, Guillaume Cartron, Dirk Hose, Giacomo Cavalli & Jerome Moreaux

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Challenges and guidelines toward 4D nucleome data and model standards.

Chromatin and cell biology

Marti-Renom MA, Almouzni G, Bickmore WA, Bystricky K, Cavalli G, Fraser P, Gasser SM, Giorgetti L, Heard E, Nicodemi M, Nollmann M, Orozco M, Pombo A, Torres-Padilla ME

Loss of PRC1 induces higher-order opening of Hox loci independently of transcription during Drosophila embryogenesis.

Chromatin and cell biology

Cheutin T, Cavalli G

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piRNAs and PIWI proteins: regulators of gene expression in development and stem cells.

mRNA Regulation and Development

Rojas-Ríos P, Simonelig M

Mrc1 and Rad9 cooperate to regulate initiation and elongation of DNA replication in response to DNA damage.

Maintenance of genome integrity during DNA replication

Bacal J, Moriel-Carretero M, Pardo B, Barthe A, Sharma S, Chabes A, Lengronne A, Pasero P

PRDM9, a driver of the genetic map.

Meiosis and recombination

Grey C, Baudat F, de Massy B

DDK Has a Primary Role in Processing Stalled Replication Forks to Initiate Downstream Checkpoint Signaling.

Maintenance of genome integrity during DNA replication

Sasi NK, Coquel F, Lin YL, MacKeigan JP, Pasero P, Weinreich M

Physiological and druggable skipping of immunoglobulin variable exons in plasma cells.

Maintenance of genome integrity during DNA replication

Ashi MO, Srour N, Lambert JM, Marchalot A, Martin O, Le Noir S, Pinaud E, Ayala MV, Sirac C, Saulière J, Moreaux J, Cogné M, Delpy L

Polycomb-Dependent Chromatin Looping Contributes to Gene Silencing during Drosophila Development.

Chromatin and cell biology

Ogiyama Y, Schuettengruber B, Papadopoulos GL, Chang JM, Cavalli G