Publications

PRDM9 Is a Major Determinant of Meiotic Recombination Hotspots in Humans and Mice

Meiosis and recombination

Baudat, F., Buard, J., Grey, C., Fledel-Alon, A., Ober, C., Przeworski, M., Coop, G., de Massy, B.

ImmunoGrid: towards agent-based simulations of the human immune system at a natural scale.

IMGT® - the international ImMunoGeneTics information system®

Halling-Brown M, Pappalardo F, Rapin N, Zhang P, Alemani D, Emerson A, Castiglione F, Duroux P, Pennisi M, Miotto O, Churchill D, Rossi E, Moss DS, Sansom CE, Bernaschi M, Lefranc MP, Brunak S, Lund O, Motta S, Lollini PL, Murgo A, Palladini A, Basford KE, Brusic V, Shepherd AJ.

Hyperglutamylation of tubulin can either stabilize or destabilize microtubules in the same cell.

Tubulin code

Wloga D, Dave D, Meagley J, Rogowski K, Jerka-Dziadosz M, Gaertig J

Two GW repeat proteins interact with Tetrahymena thermophila argonaute and promote genome rearrangement.

Epigenetic Chromatin Regulation

Bednenko J, Noto T, DeSouza LV, Siu KW, Pearlman RE, Mochizuki K, Gorovsky MA

TTLL3 Is a tubulin glycine ligase that regulates the assembly of cilia.

Tubulin code

Wloga D, Webster DM, Rogowski K, Bré MH, Levilliers N, Jerka-Dziadosz M, Janke C, Dougan ST, Gaertig J

Evolutionary divergence of enzymatic mechanisms for posttranslational polyglycylation.

Tubulin code

Rogowski K, Juge F, van Dijk J, Wloga D, Strub JM, Levilliers N, Thomas D, Bré MH, Van Dorsselaer A, Gaertig J, Janke C

Prevention of oculopharyngeal muscular dystrophy by muscular expression of Llama single-chain intrabodies in vivo.

mRNA Regulation and Development

Chartier, A., Raz, V., Sterrenburg, E., Verrips, CT., van der Maarel, SM., Simonelig, M

Non-coding RNA: a bridge between small RNA and DNA.

Epigenetic Chromatin Regulation

Kurth HM, Mochizuki K

2'-O-methylation stabilizes Piwi-associated small RNAs and ensures DNA elimination in Tetrahymena.

Epigenetic Chromatin Regulation

Kurth HM, Mochizuki K

Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription.

Maintenance of genome integrity during DNA replication

Tuduri S, Crabbé L, Conti C, Tourrière H, Holtgreve-Grez H, Jauch A, Pantesco V, De Vos J, Thomas A, Theillet C, Pommier Y, Tazi J, Coquelle A, Pasero P.

Involvement of a chromatin remodeling complex in damage tolerance during DNA replication

Maintenance of genome integrity during DNA replication

Falbo, K.B., Alabert, C., Katou, Y., Wu, S., Han, J., Wehr, T., Xiao, J., He, X., Zhang, Z., Shi, Y., Shirahige, K., Pasero, P., Shen, X.

Peripheral blood T4 cell surface CCR5 density as a marker of activity in rheumatoid arthritis treated with anti-CD20 monoclonal antibody.

Homing, immune activation and infection

Portalès P, Fabre S, Vincent T, Desmetz C, Réant B, Noël D, Clot J, Jorgensen C, Corbeau P.

Endogenous Retroviruses: Thierry Heidmann wins the 2009 Retrovirology prize.

Laboratory of Molecular Virology

Saib, A., Benkirane, M.