Publications

MCM8- and MCM9 Deficiencies Cause Lifelong Increased Hematopoietic DNA Damage Driving p53- Dependent Myeloid Tumors

Published the 01/09/2019 - Cell Reports - pmid : 0 Replication and Genome Dynamics

Malik Lutzmann, Florence Bernex, Cindy da Costa de Jesus, Dana Hodroj, Caroline Marty, Isabelle Plo, William Vainchenker, Marie Tosolini, Luc Forichon, Caroline Bret, Sophie Queille, Candice Marchive, Jean-Sébastien Hoffmann, Marcel Méchali

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In utero exposure to acetaminophen and ibuprofen leads to intergenerational accelerated reproductive aging in female mice

Published the 13/08/2019 - Communications Biology vol 2, 310 (2019) - pmid : 0 Development and Pathology of the gonad

Rossitto M, Ollivier M, Déjardin S, Pruvost A, Brun C, Marchive C, Nguyen AL, Ghettas A, Keime C, de Massy B, Poulat F, Philibert P, Boizet-Bonhoure B

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Nuclear pore density controls heterochromatin reorganization during senescence

Published the 28/07/2019 - Genes et Development Nuclear architecture in physiology and pathology

Charlene Boumendil, Priya Hari, Karl C.F. Olsen, Juan Carlos Acosta, Wendy A. Bickmore

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Phenotypic Characterization of Diffuse Large B-Cell Lymphoma Cells and Prognostic Impact.

Published the 25/07/2019 - J Clin Med - pmid : 31336593 Epigenome modifications and genomic instability in normal and malignant B cells

Devin J, Kassambara A, Bruyer A, Moreaux J, Bret C

Advances in epigenetics link genetics to the environment and disease

Published the 24/07/2019 - Nature Chromatin and cell biology

+ Chromatin and cell biology

Giacomo Cavalli and Edith Heard

Phenotype Characterization of Diffuse Large B cell Lymphoma Cells and Prognostic Impact

Published the 22/07/2019 - Journal of clinical medicine Epigenome modifications and genomic instability in normal and malignant B cells

Julie Devin, Alboukadel Kassambara, Angélique Bruyer, Jérôme Moreaux and Caroline Bret

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NF-Y controls fidelity of transcription initiation at gene promoters through maintenance of the nucleosome-depleted region.

Published the 11/07/2019 - Nat Commun. - pmid : 31296853 Biology of distal regulatory elements

Oldfield AJ*, Henriques T, Kumar D, Burkholder AB, Cinghu S, Paulet D, Bennett BD, Yang P, Scruggs BS, Lavender CA, Rivals E, Adelman K*, Jothi R*.

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Tubulin glutamylation: a skeleton key for neurodegenerative diseases.

Published the 11/07/2019 - Neural Regen Res - pmid : 31290441 Tubulin code

van der Laan S, Dubra G, Rogowski K

Non-coding RNA Transcription in Tetrahymena Meiotic Nuclei Requires Dedicated Mediator Complex-Associated Proteins.

Published the 10/07/2019 - Curr Biol - pmid : 31280995 Epigenetic Chromatin Regulation

Tian M, Mochizuki K, Loidl J

Diversification of small RNA amplification mechanisms for targeting transposon-related sequences in ciliates.

Published the 01/07/2019 - Proc Natl Acad Sci USA - pmid : 31262823 Epigenetic Chromatin Regulation

Mutazono M, Noto T, Mochizuki K.

Prospective target assessment and multimodal prediction of survival for personalized and risk-adapted treatment strategies in multiple myeloma in the GMMG-MM5 multicenter trial.

Published the 28/06/2019 - J Hematol Oncol - pmid : 31242924 Epigenome modifications and genomic instability in normal and malignant B cells

Hose D, Beck S, Salwender H, Emde M, Bertsch U, Kunz C, Scheid C, HÃ¤nel M, Weisel K, Hielscher T, Raab MS, Goldschmidt H, Jauch A, Moreaux J, Seckinger A

The hydroxymethylome of multiple myeloma identifies FAM72D as a 1q21 marker linked to proliferation.

Published the 22/06/2019 - Haematologica - pmid : 31221779 Epigenome modifications and genomic instability in normal and malignant B cells

Chatonnet F, Pignarre A, SÃ©randour AA, Caron G, Avner S, Robert N, Kassambara A, Laurent A, Bizot M, Agirre X, Prosper F, Martin-Subero JI, Moreaux J, Fest T, Salbert G

GECKO is a genetic algorithm to classify and explore high throughput sequencing data

Published the 20/06/2019 - Communications Biology Machine learning and gene regulation

Aubin Thomas, Sylvain Barriere, Lucile Broseus, Julie Brooke, Claudio Lorenzi, Jean-Philippe Villemin, Gregory Beurier, Robert Sabatier, Christelle Reynes, Alban Mancheron, William Ritchie

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Preserving Genome Integrity During the Early Embryonic DNA Replication Cycles.

Published the 24/05/2019 - Genes (Basel) - pmid : 31137726 Genome Surveillance and Stability

Kermi C, Aze A, Maiorano D

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Remodeling and destabilization of chromosome 1 pericentromeric heterochromatin by SSX proteins.

Published the 23/05/2019 - Nucleic Acids Res - pmid : 31114908 Biology of Repetitive Sequences

Traynor S, Møllegaard NE, Jørgensen MG, Brückmann NH, Pedersen CB, Terp MG, Johansen S, Dejardin J, Ditzel HJ, Gjerstorff MF

Multi-omic Profiling Reveals Dynamics of the Phased Progression of Pluripotency.

Published the 22/05/2019 - Cell Syst. - pmid : 31078527 Biology of distal regulatory elements

Yang P, Humphrey SJ, Cinghu S, Pathania R, Oldfield AJ, Kumar D, Perera D, Yang JYH, James DE, Mann M, Jothi R.

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Combination of metformin with sodium selenite induces a functional phenotypic switch of human GM-CSF monocyte-derived macrophages.

Published the 21/05/2019 - Int Immunopharmacol - pmid : 31108386 Mammalian Cell Biology

Meziane W, Mekkaoui Z, Hai I, Kacimi K, Djilali K, Touil-Boukoffa C, Lefranc G, Fernandez A, Lamb N, Mennechet F, Aribi M

The anaphase-promoting complex/cyclosome: a new promising target in diffuse large B-cell lymphoma and mantle cell lymphoma.

Published the 16/05/2019 - Br J Cancer - pmid : 31089208 Epigenome modifications and genomic instability in normal and malignant B cells

Maes A, Maes K, De Raeve H, De Smedt E, Vlummens P, Szablewski V, Devin J, Faict S, De Veirman K, Menu E, Offner F, Spaargaren M, Moreaux J, Vanderkerken K, Van Valckenborgh E, De Bruyne E