Projects Team Chromatin and cell biology

Epigenetics, the study of molecules and mechanisms that perpetuate alternative gene activity states in the context of the same DNA sequence,[...]

Transgenerational epigenetic inheritance of chromatin states: the role of Polycomb and 3D chromosome architecture
Start date: 2018-11-01, End date:[...]

The information stored in our genome is intertwined with its function, such that, when cells are submitted to specific sets of conditions, they may[...]

Polycomb group (PcG) and trithorax group (trxG) proteins are key regulators of the expression of major developmental genes. PcG proteins are able to[...]

Coordination between cellular proliferation and differentiation ensures proper tissue morphogenesis and maintains homeostasis in multicellular organisms.[...]

Epigenetic inheritance entails transmission of phenotypic traits not encoded in the DNA sequence and, in the most extreme case, transgenerational Epigenetic[...]

In this page you will find basic information on Polycomb and Trithorax proteins in epigenetic regulation; as well as the teaching material of our lab[...]