Projects Team Molecular Basis of Inflammation

Synopsis:

The CrIC project aimed at identifying the molecular mechanisms at play in the onset and maintenance of tumor promoting[...]

Nous avons montré que l’activité de transcription-inverse (RT) associée aux retro-éléments endogènes, génère des acides nucléiques immunogènes. Ces acides[...]

Genotoxic stress is a complex phenomenon engaging numerous molecular interactions and post-translational modifications, induced by genetic instability[...]

Chronic inflammation can be fueled by high fat diets that promote concerted alterations of inflammatory and metabolic pathways. We recently identified the STING[...]

Although most immunogenic nucleic acids are detected in the cytosol, the proteins mediating this recognition are, to a large extent, associated with[...]

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The research program of the FrontINove IRN is evolutive and will adapt to novel challenges emerging in the field of Immunology. Novel axis[...]