REGULATION OF GENOME STABILITY DURING EARLY EMBRYOGENESIS It has been known for a longtime that the DDR is inefficient in the early embryos, however the reasons for this regulation and the underlying molecular[...] Find out more Genome Surveillance and Stability Projects of the team
IMPLICATION OF TRANSLESION SYNTHESIS IN THE THERAPEUTIC RESISTANCE OF CANCER We have shown that ectopic expression of Rad18 in human somatic cells is sufficient to constitutively activate translesion DNA synthesis and shut down[...] Find out more Genome Surveillance and Stability Projects of the team
IDENTIFICATION OF NOVEL DDR GENES In the aim of identifying new DDR-responsive genes, we have developped an in vitro screen using protein extracts derived from Xenopus eggs and identified[...] Find out more Genome Surveillance and Stability Projects of the team
