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ANDREW OLDFIELD

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EDUCATION

2010 PhD
Université Paris VI, Pierre et Marie Curie, France. Supervised by: Dr. Claire Rougeulle.

2006 Master’s
Genomes, Cells, Development & Evolution, specialised in Genomics. Université Paris XI, Orsay, France

CURRENT POSITION

Since 2022 – Independent Project Leader. Biology of distal regulatory elements group.
Department of Genome Dynamics, Institut de Génétique Humaine, CNRS UMR9002, Université de Montpellier, France.

Since 2018 – Permanent researcher – CNRS CRCN
Department of Genome Dynamics, Institut de Génétique Humaine, CNRS UMR9002, Université de Montpellier, France.

PREVIOUS POSITIONS

2018-2022

CNRS permanent researcher: Epigenetics and Splicing group, Institute of Human Genetics, UMR9002, Montpellier, France.

Subject: The role of chromatin tri-dimensional structure in alternative splicing.

Supervised by Dr. Reini Fernandez de Luco.

2016-2018

Post-doctoral fellow: Epigenetics and Splicing group, Institute of Human Genetics, UMR9002, Montpellier, France.

Subject: The role of chromatin tri-dimensional structure in alternative splicing.

Mentored by Dr. Reini Fernandez de Luco.

2012-2016

Post-doctoral fellow: Systems Biology Group, Epigenetics and Stem Cell Biology Laboratory, NIEHS, NIH, Research Triangle Park, North Carolina, USA.

Subject: Studying the role of the NF-Y complex in the maintenance of murine embryonic stem cell cellular identity.

Mentored by Dr. Raja Jothi.

2011-2012

Post-doctoral fellow: Genome Organization and Function Laboratory, University College London Cancer Institute, London, United Kingdom.

Subject: Cohesin’s role in transcriptional regulation and tridimensional chromatin architecture.

Mentored by Dr. Suzana Hadjur.

2010-2011

Post-doctoral fellow: Laboratory of Non-coding RNAs, Differentiation and Development, Epigenetics and Cell Fate Unit, UMR7216, Université Paris VII - Diderot, France.

Subject: Study of the Xist transcriptional network in murine embryonic stem cells.

Mentored by Dr. Claire Rougeulle.

2006-2010

PhD student: Mouse Molecular Genetics Laboratory, Institut Pasteur of Paris, directed by Pr. Philip Avner (2006-2008), Laboratory of Non-coding RNAs, Differentiation and Development, Epigenetics and Cell Fate Unit, UMR7216, Université Paris VII - Diderot, France. (2009-2010).

Subject: Study of the Xist transcriptional network in murine embryonic stem cells.

Mentored by Dr. Claire Rougeulle.

2006-2009

Teaching Assistant: Cellular Biology. Université Paris VI - Pierre et Marie Curie, France.

2006

Research Assistant: Laboratory of Molecular Genetics, École Normale Supérieure of Paris. Directed by Pr. Claude Jacques.

Subject: Modifications of the histone H3 acetylation profile in the presence of toxic substances in S. Cerevisiae.

Mentored by Pr. Frédéric Devaux.

2005

Research Assistant: Department of Cellular and Molecular Medicine, Wilhelm Johannsen Centre for Functional Genome Research, University of Copenhagen, Copenhagen, Denmark.

Subject: Characterisation of chromosomal breakpoints in Crohn’s disease patients.

Mentored Pr. Zeynep Tümer.

2004

Research Assistant: Genomics Platform, Institut Pasteur of Paris, France.

Subject : Molecular typing of Acinetobacter strains from the Pasteur Institute Collection.

Mentored by Dr. Christiane Bouchier.

2003

Research Assistant : Institute of Genetics & Microbiology, UMR8621, Université Paris XI - Orsay, France.

Subject : Function of the HAP5 gene in the yeast Kluyveromyces Lactis.

Mentored by Pr. Monique Bolotin-Fukuhara.

FELLOWSHIPS

2017: Marie Sklodowska-Curie action (MSCA) Postdoctoral fellowship. Chromatin and Splicing team, department of Genome Dynamics, Institut de Génétique Humaine, CNRS UMR9002, Université de Montpellier, France.

2016: ARC Postdoctoral fellowship. Chromatin and Splicing team, department of Genome Dynamics, Institut de Génétique Humaine, CNRS UMR9002, Université de Montpellier, France.

2009: ARC 4th year of PhD funding. Non-coding RNAs, Differentiation and Development group. Epigenetics and Cell Fate Unit, CNRS UMR7216, Université de Paris, France.

2006: PhD scholarship, French ministry of research and technology. Non-coding RNAs, Differentiation and Development group. Epigenetics and Cell Fate Unit, CNRS UMR7216, Université de Paris, France.

SUPERVISION OF GRADUATE STUDENTS AND POSTDOCTORAL FELLOWS

2022: - Postdoc: Bandana Kumari. Machine learning & gene regulation team. Co-supervised with William Ritchie. Institut de Génétique Humaine, Université de Montpellier, France.

  • PhD student : Marie-Sarah Cabrillac. Chromatin and Splicing group. Co-supervised with Reini Luco, Institut de Génétique Humaine, , Université de Montpellier, France.

  • M1 student: Nicolas Gaubert. Université de Rennes I, France.

2021: - PhD student : Marie-Sarah Cabrillac. Chromatin and Splicing group. Co-supervised with Reini Luco. Institut de Génétique Humaine, Université de Montpellier, France.

  • L3 student : Victor Perreaux. École Normale Supérieure of Paris, France.

2020: - M1 student : Soumya Bouchouika. Université de Montpellier, France.

  • M2 student : Katharina Arnold. Molecular Biosciences master’s program at the EMBL, Heidelberg, Germany.

2018: - M2 student: Samira Kemiha. Université de Montpellier, France.

TEACHING ACTIVITIES
2006-2009: Teaching Assistant. Cellular Biology. Université Paris VI - Pierre et Marie Curie, France.

ORGANISATION OF SCIENTIFIC MEETINGS

2017 – present: Organizer of the weekly IGH internal seminars. In person, remotely or hybrid. Between 40 and 70 attendees. Montpellier, France.

2018: co-organizer of Chromatin meets South. 12th & 13th of June. 120 participants. Genopolys, Montpellier, France.

INSTITUTIONAL RESPONSIBILITIES

2017 – present: Organizer of the IGH internal seminars, Montpellier, France.

2020 – present: Responsible of one of the IGH cell culture rooms, Montpellier, France.

2020 – present: member of the IGH Green committee, Montpellier, France.

COMMISSIONS OF TRUST

2019 – present: Evaluator of Marie Sklodowska-Curie Actions (MSCA) Postdoctoral fellowships applications. Europe.

MAJOR COLLABORATIONS

- William Ritchie. Topic: Identifications of the determinants responsible for consecutively retained introns. Machine learning & gene regulation team, Institut de Génétique Humaine, Université de Montpellier, France.

- Tom Sexton. Topic: Understanding the role of enhancer-promoter interactions during the epithelial-to-mesenchymal transition. Spatial organization of the genome group, Functional Genomics and Cancer department, IGBMC, Strasburg, France.

- Emmanuelle Charafe-Jauffret & Christophe Ginestier. Topic: Studying chromatin accessibility and gene expression in patient-derived xenografts of human metastatic breast cancer single-cells. Epithelial stem cells and Cancer group, CRCM, Marseille, France.

- Pengyi Yang. Topic: Bioinformatic analysis of single-cell ATAC-seq and RNA-seq. Computational Systems Biology group, Children's Medical Research Institute, Charles Perkins Centre, University of Sydney, Australia.

FUNDING

2023-2026 : ANR PRC

2021-2023 : Emergence Canceropôle Grand Sud-Ouest

2022 : SIRIC/NUMEV