Heritable traits have long revolved around genomic DNA, yet emerging research redefines our understanding of inheritance. In our laboratory, we embark on a captivating journey into the world of small RNAs and their role in epigenetic inheritance, employing the model organism Caenorhabditis elegans. During my talk, I will unveil the profound influence of small RNAs in trait inheritance. I will present a compelling case study demonstrating how small RNAs gradually reduce fertility across successive generations of worms, shedding light on the intricate molecular mechanisms underpinning their intergenerational transmission. Furthermore, I will share recent results on the fascinating phenomenon of small RNAs migrating from the soma to the germline, enabling the inheritance of environmentally acquired information.
Small RNAs In Epigenetic Inheritance Chromatin and cell biology
ORGANIZED BY IGH
International Summer-School on Epigenetics from 15/07/2024 until 19/07/2024 Genopolys, Montpellier - France
Meiosis and recombinationMBHD Dpt. Seminar Series
IGH Seminar Series of the Department “Molecular basis of Human Diseases” from 02/04/2024 until 11/10/2024 11:30 - 14:00 Genopolys amphitheater
GCB&D Dpt. Seminar Series
IGH Seminar Series of the Department “Genetics, Cell Biology and Development” from 19/02/2024 until 15/11/2024 Genopolys amphitheater
Seminars
Selective autophagy of DNA lesions promotes DNA repair and cell survival
11/10/2024 11:30 Genopolys AmphitheatreIchthyosporeans and the evolution of animal embryogenesis
15/11/2024 11:30 Genopolys amphitheaterCongresses
Transcription and Genome maintenance
09/09/2024 until 13/09/2024 Roscoff, France2024 RNase H meeting
16/09/2024 until 18/09/2024 Engelthal Ingelheim, GermanyCBS2 day 2024
26/09/2024 Université Montpellier, FrTweet