Laure DUTRIEUX, Sara OVEJERO, Antoine GUILLEMIN, Miss Leriem ZELLAGUI, Elke De BRUYNE, Catharina MUYLAERT, Lien VAN HEMELRIJCK, Yea-Lih LIN, Elle LOUGHRAN, Armelle CHOQUET, Talha MAGAT, Soumya BOUCHOUIKA, Caroline BRET, Guilhem REQUIRAND, Nicolas ROBERT, Laure VINCENT, Guillaume CARTRON, Charles HERBAUX, Raphaël RODRIGUEZ, Michel COGNE, Eric RIVALS, Jean-Christophe ANDRAU, Alexandre DAVID, Philippe PASERO, and Jérôme MOREAUX

+ Maintien de l'intégrité du génome au cours de la réplication

PIM2 inhibition promotes MCL1 dependency in plasma cells involving integrated stress response-driven NOXA expression.

Publié le 03/01/2025 - Nat Commun , 16(1):256 39747141

Haas M, Cherfa S, Nguyen L, Bourgoin M, Caron G, Dessauge E, Marchand T, Delpy L, Auberger P, Moreaux J, Jacquel A, Fest T

Glofitamab plus gemcitabine and oxaliplatin (GemOx) versus rituximab-GemOx for relapsed or refractory diffuse large B-cell lymphoma (STARGLO): a global phase 3, randomised, open-label trial.

Publié le 17/11/2024 - Lancet , 404(10466):1940-1954 39550172

Abramson JS, Ku M, Hertzberg M, Huang HQ, Fox CP, Zhang H, Yoon DH, Kim WS, Abdulhaq H, Townsend W, Herbaux C, Zaucha JM, Zhang QY, Chang H, Liu Y, Cheah CY, Ghesquieres H, Simko S, Orellana-Noia V, Ta R, Relf J, Dixon M, Kallemeijn M, Mulvihill E, Huang H, Lundberg L, Gregory GP

Six-year follow-up of phase II study exploring chemo-free treatment association with idelalisib and obinutuzumab in symptomatic relapsed/ refractory patients with Waldenström's macroglobulinemia.

Publié le 05/11/2024 - Ann Hematol 39499299

Tomowiak C, Poulain S, Nudel M, Feugier P, Herbaux C, Mahé B, Morel P, Aurran T, Tournilhac O, Leprêtre S, Assaad S, Villemagne B, Casasnovas O, Lhermitte A, Roos-Weil D, Torregrosa-Diaz J, Chevret S, Leblond V, on the behalf of the FILO group

PI3Kδ activation, IL-6 overexpression, and CD37 loss cause resistance to naratuximab emtansine in lymphomas.

Publié le 08/10/2024 - Blood Adv , 8(24):6268-6281 39374583

Arribas AJ, Napoli S, Gaudio E, Herbaux C, Cannas E, Tarantelli C, Bordone-Pittau R, Cascione L, Munz N, Aresu L, Sgrignani J, Rinaldi A, Kwee I, Rossi D, Cavalli A, Zucca E, Stussi G, Stathis A, Sloss C, Davids MS, Bertoni F

KDM6A controls immunogenicity in MM.

Publié le 03/10/2024 - Blood , 144(14):1465-1467 39361299

Moreaux J

Single-hit genome editing optimized for maturation in B cells redirects their specificity toward tumor antigens.

Publié le 29/09/2024 - Sci Rep , 14(1):22432 39342013

Ueda N, Cahen M, Leonard J, Deleurme L, Dreano S, Sirac C, Galy A, Moreaux J, Danger Y, Cogné M

Pola-R-CHP or R-CHOEP for first-line therapy of younger patients with high-risk diffuse large B-cell lymphoma: a retrospective comparison of two randomized phase 3 trials.

Publié le 26/09/2024 - Leukemia , 38(12):2709-2711 39322715

Lenz G, Tilly H, Ziepert M, Altmann B, Herbaux C, Frontzek F, Nickelsen M, Lee C, Hirata J, Sahin D, Chohan S, Batlevi CL, Yan M, Morschhauser F, Schmitz N

CD38, CD39, and BCL2 differentiate disseminated forms of high-grade B-cell lymphomas in biological fluids from Burkitt lymphoma and diffuse large B-cell lymphoma.

Publié le 19/09/2024 - Cytometry B Clin Cytom 39295433

Marianini P, Lacheretz-Szablewski V, Almeras M, Moreaux J, Bret C

BHLHE41, a transcriptional repressor involved in physiological processes and tumor development.

Publié le 10/09/2024 - Cell Oncol (Dordr) 39254779

Bret C, Desmots-Loyer F, Moreaux J, Fest T

A case of refractory IgG4-related disease successfully treated with daratumumab and lenalidomide.

Publié le 24/08/2024 - Rheumatology (Oxford) 39180414

Coulomb D, Szablewski V, Robert N, Dupuy AM, Berrahouane R, Goulabchand R, Moreaux J, Maria ATJ, Herbaux C

FCGR3A F158V alleles frequency differs in multiple myeloma patients from healthy population.

Publié le 23/08/2024 - Oncoimmunology , 13(1):2388306 39175948

Constantinides M, Robert N, Multrier C, Coënon L, Campos-Mora M, Jacquard C, Gao F, Zemiti S, Presumey J, Cartron G, Moreaux J, Villalba M

Quantitative Integrative Survival Prediction in Multiple Myeloma Patients Treated With Bortezomib-Based Induction, High-Dose Therapy and Autologous Stem Cell Transplantation.

Publié le 10/07/2024 - JCO Precis Oncol , 8:e2300613 38986047

Hummel M, Hielscher T, Emde-Rajaratnam M, Salwender H, Beck S, Scheid C, Bertsch U, Goldschmidt H, Jauch A, Moreaux J, Seckinger A, Hose D

Brexucabtagene autoleucel in relapsed or refractory mantle cell lymphoma, intention-to-treat use in the DESCAR-T registry.

Publié le 20/06/2024 - Haematologica 38899352

Herbaux C, Bret C, Bachy E, Bories P, Di Blasi R, Cuffel A, Gastinne T, Lamy T, Roussel M, Bouabdallah K, Beauvais D, Cartron G, Bay JO, Blaise D, Rubio MT, Mohty M, Le Bras F, Casasnovas O, Guy J, Guidez S, Llorente CC, Hermine O, La Rochelle LD, Carras S, Guffroy B, Caillat-Zucman S, Houot R, Le Gouill S

Flow cytometric analysis of peripheral blood neutrophil myeloperoxidase expression in myelodysplastic neoplasms (MPO-MDS-Valid): protocol for a multicentre diagnostic accuracy study.

Publié le 19/06/2024 - BMJ Open , 14(6):e081200 38889946

Planta C, Bret C, Manzoni D, Lhoumeau AC, Mayeur Rousse C, Ticchioni M, Campos L, Eischen A, Gonnet N, Merle R, Seigneurin A, Paul F, Comte E, Allieri-Rosenthal A, Tondeur S, Regnart C, Jacob MC, Labarère J, Park S, Raskovalova T

Efficacy of ruxolitinib in the treatment of relapsed/refractory large granular lymphocytic leukaemia.

Publié le 19/04/2024 - Br J Haematol , 205(3):915-923 38639192

Marchand T, Pastoret C, Damaj G, Lebouvier A, Herbaux C, Moignet A, Pavlosky M, Pavlosky A, Blouet A, Eloit M, Launay V, Lebreton P, Stamatoullas A, Nilsson C, Ochmann M, Prola J, Lamy T

Long-term results of Waldenström macroglobulinaemia treatment by bendamustine and rituximab: A study on behalf of the French Innovative Leukemia Organization (FILO).

Publié le 20/03/2024 - Br J Haematol 38504454

Laribi K, Poulain S, Willems L, Merabet F, Herbaux C, Roos-Weil D, Laribi de Materre I, Roussel X, Nudel M, Tricot S, Dupuis J, Le Calloch R, Bareau B, Leblond V

An atlas of cells in the human tonsil.

Publié le 02/02/2024 - Immunity 38301653

Massoni-Badosa R, Aguilar-Fernández S, Nieto JC, Soler-Vila P, Elosua-Bayes M, Marchese D, Kulis M, Vilas-Zornoza A, Bühler MM, Rashmi S, Alsinet C, Caratù G, Moutinho C, Ruiz S, Lorden P, Lunazzi G, Colomer D, Frigola G, Blevins W, Romero-Rivero L, Jiménez-Martínez V, Vidal A, Mateos-Jaimez J, Maiques-Diaz A, Ovejero S, Moreaux J, Palomino S, Gomez-Cabrero D, Agirre X, Weniger MA, King HW, Garner LC, Marini F, Cervera-Paz FJ, Baptista PM, Vilaseca I, Rosales C, Ruiz-Gaspà S, Talks B, Sidhpura K, Pascual-Reguant A, Hauser AE, Haniffa M, Prosper F, Küppers R, Gut IG, Campo E, Martin-Subero JI, Heyn H

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Combined inhibition of Wee1 and Chk1 as a therapeutic strategy in multiple myeloma.

Publié le 21/12/2023 - Front Oncol , 13:1271847 38125947

Bruyer A, Dutrieux L, de Boussac H, Martin T, Chemlal D, Robert N, Requirand G, Cartron G, Vincent L, Herbaux C, Lutzmann M, Bret C, Pasero P, Moreaux J, Ovejero S

+ Maintien de l'intégrité du génome au cours de la réplication

Immunophenotypic portrait of leukemia-associated-phenotype markers in B acute lymphoblastic leukemia.

Publié le 01/12/2023 - Cytometry B Clin Cytom 38037221

Boris E, Theron A, Montagnon V, Rouquier N, Almeras M, Moreaux J, Bret C

RNA-sequencing based first choice of treatment and determination of risk in multiple myeloma.

Publié le 30/11/2023 - Front Immunol , 14:1286700 38035078

Emde-Rajaratnam M, Beck S, Benes V, Salwender H, Bertsch U, Scheid C, Hänel M, Weisel K, Hielscher T, Raab MS, Goldschmidt H, Jauch A, Maes K, De Bruyne E, Menu E, De Veirman K, Moreaux J, Vanderkerken K, Seckinger A, Hose D

Extreme thrombocytosis with an aggressive evolution harboring a novel variant of calreticulin (CALR) in exon 3.

Publié le 03/11/2023 - Eur J Haematol 37918825

Bonnet S, Carillo S, Legrand B, Burroni B, Lavabre-Bertrand T, Requirand G, Robert N, Fornero L, Al Mansoori A, Moreaux J, Cartron G, Gabellier L, Herbaux C

Ethnic sensitivity assessment: Polatuzumab vedotin pharmacokinetics in Asian and non-Asian patients with previously untreated diffuse large B-cell lymphoma in POLARIX.

Publié le 21/10/2023 - Clin Transl Sci , 16(12):2744-2755 37864313

Liao MZ, Deng R, Gibiansky L, Lu T, Agarwal P, Dere R, Lee C, Hirata J, Herbaux C, Salles G, Li C, Miles D

Non-Relapse Mortality after CAR T-Cell therapy for Large B-Cell Lymphoma: A LYSA Study from the DESCAR-T Registry.

Publié le 06/09/2023 - Blood Adv 37672383

Lemoine J, Bachy E, Cartron G, Beauvais D, Gastinne T, Di Blasi R, Rubio MT, Guidez S, Mohty M, Casasnovas O, Joris M, Castilla-Llorente C, Haioun C, Hermine O, Loschi M, Carras S, Bories P, Fradon T, Herbaux C, Sesques P, Le Gouill S, Morschhauser F, Thieblemont C, Houot R

EZH2 targeting induces CD38 upregulation and response to anti-CD38 immunotherapies in multiple myeloma.

Publié le 03/08/2023 - Leukemia , 37(9):1925-1928 37532787

Chemlal D, Varlet E, Machura A, Ovejero S, Requirand G, Robert N, Cartron G, Alaterre E, Bret C, Vincent L, Herbaux C, Cavalli G, Bruyer A, De Boussac H, Moreaux J

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S-adenosylmethionine biosynthesis is a targetable metabolic vulnerability in multiple myeloma.

Publié le 20/07/2023 - Haematologica 37470139

Wang Y, Muylaert C, Wyns A, Vlummens P, De Veirman K, Vanderkerken K, Zaal E, Berkers C, Moreaux J, De Bruyne E, Menu E

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Var∣Decrypt: a novel and user-friendly tool to explore and prioritize variants in whole-exome sequencing data.

Publié le 14/06/2023 - Epigenetics Chromatin , 16(1):23 37312221

Salma M, Alaterre E, Moreaux J, Soler E

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Tandem versus single haematopoietic stem cell transplant and BV maintenance in relapsed/refractory Hodgkin lymphoma: A matched cohort analysis from the LYSA.

Publié le 17/05/2023 - Br J Haematol , 202(2):379-383 37192755

Marouf A, Molinari N, Sibon D, Cottereau AS, Kanoun S, Antoine C, Debureaux PE, Cavalieri D, Fornecker LM, Casasnovas RO, Herbaux C, Amorim S, Rossi C, Bouscary D, Brice P, Ghesquieres H, Tamburini J, Deau B

3-O sulfation of syndecan-1 mediated by the sulfotransferase HS3ST3a1 enhances myeloma aggressiveness.

Publié le 16/05/2023 - Matrix Biol 37201729

Baert L, Manfroi B, Quintero M, Chavarria O, Barbon PV, Clement E, Zeller A, Van Kuppevelt T, Sturm N, Moreaux J, Tveita A, Bogen B, McKee T, Huard B

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Prospective evaluation of lymphoma response to immunomodulatory therapy criteria in GATA trial from the LYSA group.

Publié le 18/04/2023 - Blood Adv , 7(14):3735-3738 37067945

Al Tabaa Y, Casasnovas RO, Baillet C, Bachy E, Nicolas-Virelizier E, Schiano De Colella JM, Bailly C, Kanoun S, Guidez S, Gyan E, Gressin R, Morineau N, Ysebaert L, Le Gouill S, Tilly H, Houot R, Morschhauser F, Cartron G, Herbaux C

Randomized Phase III Trial Evaluating Subcutaneous Rituximab for the First-Line Treatment of Low-Tumor Burden Follicular Lymphoma: Results of a LYSA Study.

Publié le 18/04/2023 - J Clin Oncol , 41(19):3523-3533 37071836

Cartron G, Bachy E, Tilly H, Daguindau N, Pica GM, Bijou F, Mounier C, Clavert A, Damaj GL, Slama B, Casasnovas O, Houot R, Bouabdallah K, Sibon D, Fitoussi O, Morineau N, Herbaux C, Gastinne T, Fornecker LM, Haioun C, Launay V, Araujo C, Benbrahim O, Sanhes L, Gressin R, Gonzalez H, Morschhauser F, Ternant D, Xerri L, Tarte K, Pranger D

Anti-PD-1 therapy can possibly reverse CAR T cells exhaustion in DLBCL.

Publié le 05/04/2023 - Br J Haematol , 202(2):217-218 37013670

Lamure S, Herbaux C

Editorial: Transcriptional control in normal and malignant B-lymphocytes.

Publié le 27/03/2023 - Front Immunol 37051248

Jerome Moreaux, Alexander A Shtil

Preventive plasmapheresis for rituximab related flare in cryoglobulinemic vasculitis.

Publié le 07/03/2023 - J Transl Autoimmun , 6:100194 36874399

Fornero L, Kanouni T, Tudesq JJ, Pochard C, Verot P, Renier W, Gabellier L, Cartron G, Guilpain P, Herbaux C

Plain Language Summary of the iNNOVATE study: ibrutinib plus rituximab is well-tolerated and effective in people with Waldenström's macroglobulinemia.

Publié le 24/02/2023 - Future Oncol , 19(5):345-353 36815271

Buske C, Tedeschi A, Trotman J, García-Sanz R, MacDonald D, Leblond V, Mahe B, Herbaux C, Matous JV, Tam CS, Heffner LT, Varettoni M, Palomba ML, Shustik C, Kastritis E, Treon SP, Ping J, Hauns B, Arango-Hisijara I, Dimopoulos MA

The BLM helicase is a new therapeutic target in multiple myeloma involved in replication stress survival and drug resistance.

Publié le 27/12/2022 - Front Immunol , 13:983181 36569948

Ovejero S, Viziteu E, Dutrieux L, Devin J, Lin YL, Alaterre E, Jourdan M, Basbous J, Requirand G, Robert N, de Boussac H, Seckinger A, Hose D, Vincent L, Herbaux C, Constantinou A, Pasero P, Moreaux J

+ Instabilité Génétique et Cancer / Maintien de l'intégrité du génome au cours de la réplication

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LAIR1, an ITIM-Containing Receptor Involved in Immune Disorders and in Hematological Neoplasms.

Publié le 24/12/2022 - Int J Mol Sci , 23(24) 36555775

Van Laethem F, Donaty L, Tchernonog E, Lacheretz-Szablewski V, Russello J, Buthiau D, Almeras M, Moreaux J, Bret C

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Salvage therapy with brentuximab-vedotin and bendamustine for patients with R/R PTCL: a retrospective study from the LYSA.

Publié le 09/12/2022 - Blood Adv 36477770

Damaj G, Aubrais R, Bouabdallah K, Chartier L, Herbaux C, Banos A, Brice P, Sibon D, Schiano JM, Cluzeau T, Laribi K, LE Calloch R, Bellal M, Delapierre B, Daguindau N, Amorim S, Agbetiafa K, Chauchet A, Besson C, Durot E, Bonnet C, Fouillet L, Bijou F, Tournilhac O, Gaulard P, Parrens MC

Targeting the β(2) -adrenergic receptor increases chemosensitivity in multiple myeloma by induction of apoptosis and modulating cancer cell metabolism.

Publié le 18/10/2022 - J Pathol 36245401

Satilmis H, Verheye E, Vlummens P, Oudaert I, Vandewalle N, Fan R, Knight JM, De Beule N, Ates G, Massie A, Moreaux J, Maes A, De Bruyne E, Vanderkerken K, Menu E, Sloan EK, De Veirman K

miRNA profile at diagnosis predicts treatment outcome in patients with B-chronic lymphocytic leukemia: A FILO study

Publié le 17/10/2022 - Front Immunol 36325355

Isabelle Duroux-Richard, Anne-Laure Gagez, Elina Alaterre, Rémi Letestu, Olfa Khalifa, Christian Jorgensen, Stéphane Leprêtre, Emmanuelle Tchernonog, Jérôme Moreaux, Guillaume Cartron, Florence Apparailly

Ibrutinib as a treatment of hematologic autoimmune disorders in patients with indolent B-cell lymphoma.

Publié le 02/09/2022 - Eur J Haematol , 109(6):719-727 36048142

Daniel A, Ghez D, Ravaiau C, Cavalieri D, Tournilhac O, Herbaux C, Roriz M, Wemeau M, Guillet S, Bossard JB, Hélène D, Kaphan E, Caroline R, Florence L, Pierache A, Michel M, Godeau B, Terriou L

Inhibition of the Protein Arginine Methyltransferase PRMT5 in High-Risk Multiple Myeloma as a Novel Treatment Approach.

Publié le 28/06/2022 - Front Cell Dev Biol , 10:879057 35757005

Vlummens P, Verhulst S, De Veirman K, Maes A, Menu E, Moreaux J, De Boussac H, Robert N, De Bruyne E, Hose D, Offner F, Vanderkerken K, Maes K

Therapy-related Myeloid Neoplasms in Patients With Chronic Lymphocytic Leukemia Who Received FCR/FC as Frontline Therapy.

Publié le 25/06/2022 - Hemasphere , 6(6):e716 35747848

Laribi K, Baugier de Materre A, Ghez D, Dartigeas C, Tomowiak C, Mahé B, Micol JB, Merabet F, Leprêtre S, Herbaux C, Ysebaert L, Le Calloch R, Willems L, Voldoire M, Roos-Weil D, Bravetti C, Touileb Y, Davi F, Nguyen-Khac F, Maloum K, Béné MC

Can nivolumab alone cure patients with relapse or refractory Hodgkin lymphoma? A 5-year analysis of the French early access program (EPA).

Publié le 22/04/2022 - Br J Haematol , 198(1):203-206 35445392

Manson G, Herbaux C, Schiano JM, Casasnovas O, Stamatoullas A, Deau B, Schmitt A, Regny C, Bouabdallah K, Chauchet A, Ghesquieres H, Tempescul A, Dulery R, Nicolas-Virelizier E, Delmer A, Borel C, Dercle L, Brice P, Houot R, Lymphoma Study Association (LYSA)

The NADPH oxidase NOX2 is a marker of adverse prognosis involved in chemoresistance of acute myeloid leukemias.

Publié le 18/02/2022 - Haematologica , 107(11):2562-2575 35172562

Paolillo R, Boulanger M, Gâtel P, Gabellier L, De Toledo M, Tempé D, Hallal R, Akl D, Moreaux J, Baik H, Gueret E, Recher C, Sarry JE, Cartron G, Piechaczyk M, Bossis G

PIM2 kinase has a pivotal role in plasmablast generation and plasma cell survival, opening up novel treatment options in myeloma.

Publié le 03/02/2022 - Blood , 139(15):2316-2337 35108359

Haas M, Caron G, Chatonnet F, Manenti S, Alaterre E, Devin J, Delaloy C, Bertolin G, Viel R, Pignarre A, Llamas-Gutierrez F, Marchalot A, Decaux O, Tarte K, Delpy L, Moreaux J, Fest T

Angiogenic factors could help us to define patients obtaining complete response with undetectable minimal residual disease in untreated CLL patients treated by FCR: results from the CLL2010FMP, a FILO study.

Publié le 23/11/2021 - Leuk Lymphoma , 62(13):3160-3169 34806520

Gagez AL, Paul F, Alaterre E, Gouilleux-Gruart V, Tuaillon E, Lepretre S, Ternant D, Letestu R, Moreaux J, Cartron G

RNA-Sequencing-Based Transcriptomic Score with Prognostic and Theranostic Values in Multiple Myeloma.

Publié le 24/10/2021 - J Pers Med , 11(10) 34683129

Alaterre E, Vikova V, Kassambara A, Bruyer A, Robert N, Requirand G, Bret C, Herbaux C, Vincent L, Cartron G, Elemento O, Moreaux J

Ibrutinib Plus Rituximab Versus Placebo Plus Rituximab for Waldenström's Macroglobulinemia: Final Analysis From the Randomized Phase III iNNOVATE Study.

Publié le 05/10/2021 - J Clin Oncol , 40(1):52-62 34606378

Buske C, Tedeschi A, Trotman J, García-Sanz R, MacDonald D, Leblond V, Mahe B, Herbaux C, Matous JV, Tam CS, Heffner LT, Varettoni M, Palomba ML, Shustik C, Kastritis E, Treon SP, Ping J, Hauns B, Arango-Hisijara I, Dimopoulos MA

Targeting the methyltransferase SETD8 impairs tumor cell survival and overcomes drug resistance independently of p53 status in multiple myeloma.

Publié le 18/09/2021 - Clin Epigenetics , 13(1):174 34530900

Herviou L, Ovejero S, Izard F, Karmous-Gadacha O, Gourzones C, Bellanger C, De Smedt E, Ma A, Vincent L, Cartron G, Jin J, De Bruyne E, Grimaud C, Julien E, Moreaux J

The microenvironment of DLBCL is characterized by noncanonical macrophages recruited by tumor-derived CCL5.

Publié le 14/09/2021 - Blood Adv , 5(21):4338-4351 34516642

Manfroi B, De Grandis M, Moreaux J, Tabruyn S, Mayol JF, Quintero M, Righini C, Sturm N, Aurrand-Lions M, Huard B

Clinical and Product Features Associated with Outcome of DLBCL Patients to CD19-Targeted CAR T-Cell Therapy.

Publié le 11/09/2021 - Cancers (Basel) , 13(17) 34503088

Lamure S, Van Laethem F, De Verbizier D, Lozano C, Gehlkopf E, Tudesq JJ, Serrand C, Benzaoui M, Kanouni T, Quintard A, De Vos J, Tchernonog E, Platon L, Ayrignac X, Ceballos P, Sirvent A, François M, Guedon H, Quittet P, Mongellaz C, Conte A, Herbaux C, Bret C, Taylor N, Dardalhon V, Cartron G

Transcription/Replication Conflicts in Tumorigenesis and Their Potential Role as Novel Therapeutic Targets in Multiple Myeloma.

Publié le 08/08/2021 - Cancers (Basel) , 13(15) 34359660

Dutrieux L, Lin YL, Lutzmann M, Rodriguez R, Cogné M, Pasero P, Moreaux J

Discovery of candidate DNA methylation cancer driver genes.

Publié le 10/05/2021 - Cancer Discov 33972312

Pan H, Renaud L, Chaligne R, Bloehdorn J, Tausch E, Mertens D, Fink AM, Fischer K, Zhang C, Betel D, Gnirke A, Imielinski M, Moreaux J, Hallek M, Meissner A, Stilgenbauer S, Wu CJ, Elemento O, Landau DA

en savoir plus

Obinutuzumab and idelalisib in symptomatic patients with relapsed/refractory Waldenström macroglobulinemia.

Publié le 08/05/2021 - Blood Adv , 5(9):2438-2446 33961019

Tomowiak C, Poulain S, Herbaux C, Perrot A, Mahé B, Morel P, Aurran T, Tournilhac O, Leprêtre S, Assaad S, Villemagne B, Casasnovas O, Nollet D, Roos-Weil D, Chevret S, Leblond V

G9a/GLP targeting in MM promotes autophagy-associated apoptosis and boosts proteasome inhibitor-mediated cell death.

Publié le 04/05/2021 - Blood Adv , 5(9):2325-2338 33938943

De Smedt E, Devin J, Muylaert C, Robert N, Requirand G, Vlummens P, Vincent L, Cartron G, Maes K, Moreaux J, De Bruyne E

RNA-sequencing data-driven dissection of human plasma cell differentiation reveals new potential transcription regulators.

Publié le 08/04/2021 - Leukemia , 35(5):1451-1462 33824465

Kassambara A, Herviou L, Ovejero S, Jourdan M, Thibaut C, Vikova V, Pasero P, Elemento O, Moreaux J

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Immunotherapy perspectives in the new era of B-cell editing.

Publié le 24/03/2021 - Blood Adv , 5(6):1770-1779 33755093

Ueda N, Cahen M, Danger Y, Moreaux J, Sirac C, Cogné M

Sara Ovejero, Jerome Moreaux

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Role of Polycomb Complexes in Normal and Malignant Plasma Cells.

Publié le 01/11/2020 - Int J Mol Sci , 21(21) 33126754

Varlet E, Ovejero S, Martinez AM, Cavalli G, Moreaux J

A Retrospective Comparison of DLI and gDLI for Post-Transplant Treatment.

Publié le 16/07/2020 - J Clin Med , 9(7) 32664688

Lamure S, Paul F, Gagez AL, Delage J, Vincent L, Fegueux N, Sirvent A, Gehlkopf E, Veyrune JL, Yang LZ, Kanouni T, Cacheux V, Moreaux J, Bonafoux B, Cartron G, De Vos J, Ceballos P

Characterization of immortalized human islet stromal cells reveals a MSC-like profile with pancreatic features.

Publié le 19/04/2020 - Stem Cell Res Ther , 11(1):158 32303252

Villard O, Armanet M, Couderc G, Bony C, Moreaux J, Noel D, De Vos J, Klein B, Veyrune JL, Wojtusciszyn A

[CD38 antibodies in multiple myeloma].

Publié le 07/01/2020 - Med Sci (Paris) , 35(12):1001-1004 31903907

Moreaux J

Maternal embryonic leucine zipper kinase is a novel target for diffuse large B cell lymphoma and mantle cell lymphoma.

Publié le 20/11/2019 - Blood Cancer J , 9(12):87 31740676

Maes A, Maes K, Vlummens P, De Raeve H, Devin J, Szablewski V, De Veirman K, Menu E, Moreaux J, Vanderkerken K, De Bruyne E

Phenotypic Characterization of Diffuse Large B-Cell Lymphoma Cells and Prognostic Impact.

Publié le 25/07/2019 - J Clin Med , 8(7) 31336593

Devin J, Kassambara A, Bruyer A, Moreaux J, Bret C

Prospective target assessment and multimodal prediction of survival for personalized and risk-adapted treatment strategies in multiple myeloma in the GMMG-MM5 multicenter trial.

Publié le 28/06/2019 - J Hematol Oncol , 12(1):65 31242924

Hose D, Beck S, Salwender H, Emde M, Bertsch U, Kunz C, Scheid C, Hänel M, Weisel K, Hielscher T, Raab MS, Goldschmidt H, Jauch A, Moreaux J, Seckinger A

The hydroxymethylome of multiple myeloma identifies FAM72D as a 1q21 marker linked to proliferation.

Publié le 22/06/2019 - Haematologica , 105(3):774-783 31221779

Chatonnet F, Pignarre A, Sérandour AA, Caron G, Avner S, Robert N, Kassambara A, Laurent A, Bizot M, Agirre X, Prosper F, Martin-Subero JI, Moreaux J, Fest T, Salbert G

The anaphase-promoting complex/cyclosome: a new promising target in diffuse large B-cell lymphoma and mantle cell lymphoma.

Publié le 16/05/2019 - Br J Cancer , 120(12):1137-1146 31089208

Maes A, Maes K, De Raeve H, De Smedt E, Vlummens P, Szablewski V, Devin J, Faict S, De Veirman K, Menu E, Offner F, Spaargaren M, Moreaux J, Vanderkerken K, Van Valckenborgh E, De Bruyne E

In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells.

Publié le 09/02/2019 - J Vis Exp , (143) 30735200

Jourdan M, de Boussac H, Viziteu E, Kassambara A, Moreaux J

Veronika Vikova, Michel Jourdan, Nicolas Robert, Guilhem Requirand, Stéphanie Boireau, Angélique Bruyer, Laure Vincent, Guillaume Cartron, Bernard Klein, Olivier Elemento, Alboukadel Kassambara, Jérôme Moreaux

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BrdU incorporation in multiparameter flow cytometry: A new cell cycle assessment approach in multiple myeloma.

Publié le 13/11/2018 - Cytometry B Clin Cytom 30417559

Requirand G, Robert N, Boireau S, Vincent L, Seckinger A, Bouhya S, Ceballos P, Cartron G, Hose D, Klein B, Moreaux J

Tumor-associated neutrophils correlate with poor prognosis in diffuse large B-cell lymphoma patients.

Publié le 07/07/2018 - Blood Cancer J , 8(7):66 29977076

Manfroi B, Moreaux J, Righini C, Ghiringhelli F, Sturm N, Huard B

Analysis of Global Gene Expression Profiles.

Publié le 26/05/2018 - Methods Mol Biol , 1792:157-166 29797258

Kassambara A, Moreaux J

Vanessa Szablewski, Caroline Bret, Alboukadel Kassambara, Julie Devin, Guillaume Cartron, Valérie Costes-Martineau and Jérôme Moreaux

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Angélique Bruyer, Hugues de Boussac, Thibaut Martin, Alboukadel Kassambara, Nicolas Robert, Hose D, Anja Seckinger, Philippe Pasero, Jérôme Moreaux

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Angélique Bruyer, Hugues de Boussac, Thibaut Martin, Alboukadel Kassambara, Nicolas Robert, Hose D, Anja Seckinger, Philippe Pasero, Jérôme Moreaux

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Elina Alaterre, Sebastien Raimbault, Hartmut Goldschmidt, Salahedine Bouhya, Guilhem Requirand, Nicolas Robert, Stéphanie Boireau, Anja Seckinger, Dirk Hose, Bernard Klein and Jérôme Moreaux

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Elina Alaterre, Sebastien Raimbault, Jean-Michel Garcia,Thierry Reme,Guilhem Requirand, Bernard Klein, and Jerome Moreaux

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Alboukadel Kassambara, Michel Jourdan, Angelique Bruyer, Nicolas Robert, Veronique Pantesco, Olivier Elemento, Bernard Klein and Jerome Moreaux

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RECQ1 helicase is involved in replication stress survival and drug resistance in multiple myeloma

Publié le 10/02/2017 - Leukemia , doi: 10.1038/leu.2017.54 28186131

E Viziteu, B Klein, J Basbous, Y-L Lin, C Hirtz, C Gourzones, L Tiers, A Bruyer, L Vincent, C Grandmougin, A Seckinger, H Goldschmidt, A Constantinou, P Pasero, D Hose, J Moreaux

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Michel Jourdan, Maïlys Cren, Peter Schafer, Nicolas Robert, Christophe Duperray, Laure Vincent, Patrice Ceballos, Guillaume Cartron, Jean-François Rossi, Jérôme Moreaux, Rajesh Chopra, Bernard Klein

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Caroline Bret, Elena Viziteu, Alboukadel Kassambara & Jerome Moreaux

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Chetomin, targeting HIF-1a/p300 complex, exhibits antitumour activity in multiple myeloma

Publié le 11/02/2016 - British Journal of Cancer , doi: 10.1038/bjc.2016.20 26867162

Elena Viziteu, Camille Grandmougin, Hartmut Goldschmidt, Anja Seckinger, Dirk Hose, Bernard Klein, Jerome Moreaux

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Caroline Bret, Bernard Klein, Guillaume Cartron, Jean-François Schved, Angelos Constantinou, Philippe Pasero, Jérôme Moreaux

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Laurie Herviou, Giacomo Cavalli, Guillaume Cartron, Bernard Klein and Jérôme Moreaux

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Alboukadel Kassambara, Thierry Rème, Michel Jourdan, Thierry Fest, Dirk Hose, Karin Tarte, Bernard Klein

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Caroline Bret, Bernard Klein and Jérôme Moreaux

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Caroline Bret, Bernard Klein and Jérôme Moreaux

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Caroline Bret, Bernard Klein, and Jérôme Moreaux

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Elias Bou Samra, Bernard Klein, Thérèse Commes, and Jérôme Moreaux

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Jérôme Moreaux, Thierry Rème, Wim Leonard, et al.

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A high-risk signature for patients with multiple myeloma established from the molecular classification of human myeloma cell lines.

Publié le 01/04/2011 - Haematologica , 96(4):574-82 21173094

Moreaux J, Klein B, Bataille R, Descamps G, Maïga S, Hose D, Goldschmidt H, Jauch A, Rème T, Jourdan M, Amiot M, Pellat-Deceunynck C

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