Heritable traits have long revolved around genomic DNA, yet emerging research redefines our understanding of inheritance. In our laboratory, we embark on a captivating journey into the world of small RNAs and their role in epigenetic inheritance, employing the model organism Caenorhabditis elegans. During my talk, I will unveil the profound influence of small RNAs in trait inheritance. I will present a compelling case study demonstrating how small RNAs gradually reduce fertility across successive generations of worms, shedding light on the intricate molecular mechanisms underpinning their intergenerational transmission. Furthermore, I will share recent results on the fascinating phenomenon of small RNAs migrating from the soma to the germline, enabling the inheritance of environmentally acquired information.
Small RNAs In Epigenetic Inheritance Chromatine et Biologie Cellulaire
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