embryogenèse précoce Genome Surveillance and Stability

Early embryos show signs of genomic instability as well as the presence of mutations whose origin was unknown until now.

In this article, published in the journal Nucleic Acids Research, scientists were able to identify a molecular mechanism responsible, and showed that it is the DNA damage tolerance system, which could also contribute to variations in genetic background between individuals.

Read the publication in the journal Nucleic Acids Research