Regulation of innate immunity by Nrf2
van der Horst D, Carter-Timofte ME, van Grevenynghe J, Laguette N, Dinkova-Kostova AT, Olagnier D
Molecular bases of human diseases
Inflammation is a normal reaction of the immune system in response to infections or tissue damage. It plays a pivotal role in triggering adaptive immune responses. However, unresolved inflammation is pervasive and fosters several etiologically distinct human pathologies that present with a broad range of symptoms. Such pathologies include cancer, auto-inflammatory and auto-immune disorders, but also metabolic diseases.
The Molecular Basis of Inflammation team studies the molecular mechanisms involved in the initiation, maintenance, and resolution of inflammation. To decipher how deregulation of these processes promote pathologies, we study inflammatory responses at several scales:
To achieve these aims, the Molecular Basis of Inflammation team uses and develops techniques ranging from nanotechnologies, single-cell transcriptomics, to in vivo phenotyping. We develop interdisciplinary approaches around these themes through networks and collaborations at national (https://www.innasco.fr/) and international (https://frontinov.cnrs.fr/) levels.
The “Molecular Basis of Inflammation” team welcomes applications from research scientists and engineers willing to implement new technologies in a fast-evolving area of research.
Contact: Nadine.Laguette@igh.cnrs.fr
van der Horst D, Carter-Timofte ME, van Grevenynghe J, Laguette N, Dinkova-Kostova AT, Olagnier D
Vila IK, Guha S, Kalucka J, Olagnier D, Laguette N.
Clara Taffoni, Johanna Marines, Hanane Chamma, Mathilde Saccas, Amel Bouzid, Soumyabrata Guha, Ana-Luiza Chaves Valadao, Katarzyna Polak, Maguy Del Rio, Celine Gongora, Donovan Pineau, Jean-Philippe Hugnot, Karima Kissa, Laura Fontenille, Fabien P. Blanchet, Isabelle K. Vila, Nadine Laguette
Chamma H, Guha S, Laguette N, Vila IK
Hanane Chamma, Isabelle K Vila, Clara Taffoni, Andrei Turtoi, Nadine Laguette
Isabelle K.Vila, Hanane Chamma, Alizée Steer, Mathilde Saccas, Clara Taffoni, Evgenia Turtoi, Line S.Reinert, Saqib Hussain, Johanna Marines, Lei Jin, Xavier Bonnefont, Mathieu Hubert, Olivier Schwartz, Soren R.Paludan, Gaetan Van Simaeys, Gilles Doumont, Bijan Sobhian, Dimitrios Vlachakis, Andrei Turtoi, Nadine Laguette
Laguette N, Langevin C, Olagnier D, Torraca V, Vanpouille-Box C, Verrier ER.
Taffoni C, Steer A, Marines J, Chamma H, Vila IK, Laguette N
Isabelle K Vila , Maxence Fretaud , Dimitrios Vlachakis, Nadine Laguette, Christelle Langevin
J. Guerra, A.-L. Valadao, D. Vlachakis, K. Polak, I. K. Vila, C. Taffoni, T. Prabakaran, A. S. Marriott, R. Kaczmarek, A. Houel, B. Auzemery,S. Déjardin,P. Boudinot, B. Nawrot, N. J. Jones, S. R. Paludan, S. Kossida, C. Langevin and N. Laguette
Perkovska S, Méjean C, Ayoub MA, Li J, Hemery F, Corbani M, Laguette N, Ventura MA, Orcel H, Durroux T, Mouillac B, Mendre C
Bregnard, C, Guerra, J, Dejardin, S, Passalacqua, F, Benkirane, M, Laguette, N
Laguette N, Benkirane M.
Laguette,N., Bregnard, C., Hue, P., Basbous, J., Yatim, A., Larroque, M., Kirchhoff, F., Constantinou, A., Sobhian, B., Benkirane, M.
Brégnard C, Benkirane M, Laguette N.
Defended by Johanna MARINES under the supervision of Dr. Karima Kissa & Dr. Nadine Laguette